|
| 北京老年妇女脊椎骨折的流行病学研究 |
| Vertebral osteoporosis of women in Beijing，China |
| |
| DOI： |
| 中文关键词: 脊椎骨折 患病率 流行病学 |
| 英文关键词:Vertebral Fracture Morbidity rate Prevalence Epidemiology |
| 基金项目: |
|
| 摘要点击次数: 983 |
| 全文下载次数: 868 |
| 中文摘要: |
| 脊椎压缩性骨折是老年妇女骨质疏松常见的并发症之一，严重影响老年妇女的健康和生活
量。本研究目的是要得出我国北京地区妇女脊椎骨折的患病率并与西方国家进行比较，分析我国妇女脊椎骨折的危险因素及其后果，从而更好预防。1993年6月至1994年5月，在北京四个城区随机抽样选出402名50岁以上妇女进行了脊椎侧位相，腰椎和髋骨骨密度测量，体力活动和平衡能力等功能试验。结果显示；北京50岁以上妇女脊椎骨折总患病率为15%，年龄越大骨折率越高。经年龄标化后的脊椎骨折患病率较美国白人妇女低5.5% 。中国妇女椎体比美国妇女小，腰椎骨密度比白人低15%。骨密度低，既往骨折史及缺乏体力活动均明显增加脊椎骨折的危险。有脊椎骨折妇女的平均身高较无骨折妇女矮1.5cm，活动和平衡能力均低于非骨折妇女。结论：北京老年妇女脊椎骨折率略低于美国白人妇女。骨密度低，其它骨折史和缺乏适当的体力活动使脊椎骨折的危险性增加。 |
| 英文摘要: |
| It is estimated that one fourth of the world’s postmenopausal women live in China，there
Has been no population-based study of osteoporosis in this country. From June1993 to May1994, a population-based study of osteoporosis was conducted in Beijing. A random sample of 2113 women age 50 or older living in Beijing were interviewed．A random sample of 402 of them were further drown to complete an additional interviews about potential risk factors and effects of vertebral fracture;3-day diet records; exams of height，weight，functional reach (a balance test)，timed chair stands，BMD of hip and spine and lateral spine films taken in accord with international standards．Vertebral dimensions were measured at UCFS using computer-assisted morphometry. Beijing women had 15% lower spine BMD than Caucasian women in SOF(P<0.0001). The prevalence of vertebral fractures increased from 4.9% in 50-59 years old to 36.6% in 80+years old Beijing women，5.5% lower than agestandardized rates in Minnesota women. In age-adjusted logistic models，the risk of vertebral fracture increased 2.4 fold(95% CI1.7，3.5)for each SD decrease in spine BMD．Any prior non-spine fracture increased the risk of vertebral fracture OR=2.2(1.1，4.3)and heavy
Physical labor decreased risk OR=0.1(0.03，0.5)．Adjusting for age，Beijing women with vertebral fractures were1.5cm shorter，had more difficulty climbing steps，7% poorer functional reach，20% slower chair stands(P<0.01)than women without fractures．Conclusion：Compared with Caucasian US
women，Beijing women have substantially lower BMD but similar rates of vertebral fracture．Low BMD，previous fracture，and intensity of occupational labor are strong risk factors for fracture in Chinese women，and these fractures are associated with height loss and impairments of physical function. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |