63例QCT腰椎骨骨密度测量与DTX-200双能X前臂骨骨密度测量对比分析
The comparing analysis between the bone mineral density measurement at the lumbar vertebra with QCT and at the forearm with DTX-200 in 63 cases
  
DOI:
中文关键词:  定量CT(QCT)  腰椎骨  前臂骨  双能X线(DTX-200)  骨密度
英文关键词:Quantitative CT(QCT)  Lumbar vertebra  Forearm bone  Duel—energy X.ray(DTX-200)  Bone mineral density
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作者单位
杨鸿兵,郭美灵,何旭颖,王超,张继,宋岳 密云县中医医院,北京,101500 
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中文摘要:
      目的 对比同一组检测者,使用DTX-200双能x线骨密度仪测量前臂骨骨密度(hone mineral density,BMD)与QCT测量腰椎骨骨密度的测定结果,发现不同设备,不同部位骨密度测量的差异性和相关性.方法 选取志愿者63例(男性19例,女性43例),分别用DTX-200双能X线骨密度仪测量前臂骨BMD值和T值(n=63),再用QCT测量腰椎骨的BMD值和T值(n=63).分别以QCT测量腰椎骨T值、DTX-200双能X线测量前臂骨T值,进行骨质疏松症诊断(诊断标准1994年WHO制定,T值≥-1.0SD为骨量正常,-2.5SD<T值<-1.0SD为骨量减低,T值≤-2.5SD为骨质疏松).用SPSS13.0软件对DTX-200和QCT测量的BMD值和T值,年龄进行相关性分析,对两组骨质疏松诊断结果分别进行一致性分析.结果 两种设备的检测结果BMD均与年龄呈负相关性,相同年龄段QCT测得的BMD较DTX-200测得的BMD要低,40岁以后更为明显,DTX-200与QCT测量的BMD值的相关系数=0.554(P<0.01),二者骨质疏松症总体诊断符合率为52.4%.结论 DTX-200双能X线测量前臂骨BMD值与QCT测量腰椎骨BMD值密切相关,目前直接使用WHO制定的诊断标准,对QCT与DTX-200的测量结果进行骨质疏松症的诊断是否合适有待进一步探讨,不同的检测设备,不同的检查部位应有不同的诊断标准或换算系数.
英文摘要:
      Abstract:Objective To compare the bone mineral density(BMD)results between the measurement at the hmbar vertebra with QCT and at the forearm with DTX-200 DXA.and to find the difference and the correlation of BMD among different equipments and measuring sites.Methods Forearm BMDs and T scores of 63 volunteers(19 males and 43 females)were measured using DTX-200 DXA.The BMDs and T scores of the lumbar vertebra were measured using QCT.The diagnosis of osteoporosis was made accordingly.BMDs measured with DXA and QCT were analyzed using SPSS 13.0 software and correlated with age.The consistency of osteoporosis diagnosis in both groups was analyzed.Results BMDs measured with the two equipments were all negatively correlated with aging.The BMD measured with QCT was lower than that measured with DTX-200 in the same age group,and this was more evident in over 40 years old age group.The correlation Coefficient of the BMD measured with DTX.200 and QCT was 0.554(P<0.01).The total consistency of osteoporosis diagnosis was 52.4%.Conclusion There is close relationship between the BMD measured at the forearm bone with DTx-200 DxA and the BMD measured at the lumbar vertebra with QCT.It needs to be explored if the osteoporosis diagnosis can be made with the measurement with either QCT or DTX-200 according to the WHO diagnostic criteria.There should be different diagnosis criteria or exchange coefficient available for different measurement equipments and measurement sites.
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