常见妇科疾病引起的雌激素水平变化与骨转换的关系
The relationship between the estrogen level in patients with common gynecological diseases and the bone turnover
  
DOI:
中文关键词:  骨转换  骨密度  雌激素
英文关键词:Bone turnover  BMD  Estrogen
基金项目:
作者单位
范璐 林华 210008南京南京大学医学院附属鼓楼医院代谢性骨病中心 
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中文摘要:
      女性常见的妇科疾病如子宫内膜异位症、子宫内膜癌、乳腺癌、Sheehan综合征等,其病程中体内雌激素水平变化,直接或间接地影响骨转换水平,导致骨量变化。本文研究不同疾病状态下,疾病本身因素或手术及药物治疗对女性卵巢功能和雌激素水平的影响,从而影响骨转换率,导致继发性骨质疏松。有助于预防和治疗女性激素相关性骨量下降和骨质疏松,提高女性患者的生活质量。
英文摘要:
      Abstract:The estrogen level in women varies in some gynecological disease courses.These diseases include endometriosis,endometrial cancer,breast cancer,and Sheehan’s syndrome.The variety directly or indirectly influences the level of bone turnover,leading to a change in bone mass.This article studies the effect of the diseases alone or the treatment using surgery and medicine on ovarian function and estrogen level under different disease status,and further on bone turnover rate that causes secondary osteoporosis.The study may contribute to prevention and treatment of osteoporosis due to female hormone-related bone loss,and to improve life quality of women.
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