|
| 糖代谢异常的代谢综合征老年男性骨密度及体脂含量特点分析 |
| The feature of bone mineral density and body fat in elderly males with metabolic syndrome ofabnormal glucose metabolism |
| 投稿时间：2012-01-20 |
| DOI： |
| 中文关键词: 糖尿病 代谢综合征 骨质疏松症 体成分 |
| 英文关键词:Diabetes mellitus Metabolic syndrome Osteoporosis Body composition |
| 基金项目: |
|
| 摘要点击次数: 1550 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的探讨糖代谢异常的代谢综合征(MS)患者骨密度(BMD)与体脂百分含量(％fat)的特
点。方法随机选取门诊符合标准的老年患者，完成问卷调查、生化、骨代谢相关指标测定，双能X
线吸收法测定BMD及％fat。按中国精尿病学会(Chinese Diabetes Society，CDS)的MS诊断标准，分为
MS组与非MS(NMS)组，按WHO骨质疏松(OP)的诊断标准分为骨量正常组，低骨营组及OP组。比
较组问差异，分析MS相关危险因索。结果该人群MS患病率为69．03％．，骨质疏松的患病率为
7．74％，低骨量患病率为35．48％。MS组骨量正常的百分率高于NMS组，骨质疏松的百分率低于
NMS组，P值接近0．05(P=0．06)。MS组各部分％fat均高于NMS组(P<0．01)。在骨量正常、低骨
量、0P三组间，年龄逐渐增大(P<0．0I)，BMI在OP组显著低于其他两组。A区％fat与G区％fat比
值(A／G)在正常组显著高于OP组(P‘0．01)。Spearman相关分析显示，MS与股骨颈、全髋、腰椎各
部位BMD的相关系数分别为0．11、0．13、0．17，但只有腰椎达到统计学差异(P<0．05)。MS与A
区％fat，G区％fat，全身％fat以及A／G相关系数分别为0．53，0．33，0．51，0．24，P值均<0．01。
logistic逐步回归分析显示，BMI，A区％fat和cr为Ms的独立危险因素。结论该组人群MS以及骨
量异常(OP及低骨量)患病率高。MS患者BMD和A区％fat、A／G高于NMS患者，OP患病率低于
NMS患者。代表腹部脂肪聚集的A区％fat是MS的独立危险因素。 |
| 英文摘要: |
| Obiective To explore the characteristics of bone mineral density and body fat in elderly males
with metabolic syndrome(MS)of abnormal shcose metabolism．Methods Elderly male patients were
randomly selected to conduct the questionnaire，biochemical measurements，and measurement of factors
related to bone metabolism．The bone mineral density(BMD)and body fat were measured by dual-energy
X·ray absorptiometry．The patients were divided into the MS group and non·MS(NMS)group according tO
the diagnostic standard of Chinese Diabetes Society．They were also divided into the normal bone ma8B
group．osteopenia group，and osteoporosis(OP)group according to the diagnostic standard of WHO．The
differences among these groups were compared and the risk factors for MS were analyzed．Results MS，
OP，and osteopenia prevalence in this study were 69．03％，7．74％，and 35．48％，respectively．The
percentage of normal bone mass in MS group was higher than that in NMS group．The percentage of
osteoporesis in MS group was lower than that in NMS group(P=0．06)．The percentage of fat of all parts in
MS group was higher than that in NMS group(P<0．Oi)．The age gradually increased among uornlal bone
mass，ostenpenia，and OP groups(P<0．01)．Body mass index(BMI)of patients in OP group WaS
signifieantly lower than that in the other two groups．The rate of the fat percentage in Android area to Gynoid
area(A／G)of patients in normal group was significantly higher than that in the OP group(P<0．01)．Theresults of Spearman correlation analysis showed that the correlation COemeients between MS and BMD of the
neck of femur，hip，and lumbar were 0．1 I，0．13，and 0．17，respectively，but only the correlation
coefficient of lumbar was statistically significant(尸<0．05)．The correlation coefficients between MS and
the fat percentage ofAndroid area，Gynoid area，total body，and A／G were 0．53，0．33．0．51，and 0．24，
respectively(P<0．01)．The results of logistic regressive analysis showed that BMI，the fat percentage of
Android area，and the creatinine were independent risk factors for MS．Conclusion The prevalence of MS
and bone mass abnormality in this group is high．BMD，the fat percent of Android al'ca，and A／G in MS
group are higher than those in the NMS group．However，the prevalence of OP in the MS group is lower than
that in the NMS group．The fat percentage of Android area as aggregation of abdominal fat is an independent
risk foctor far MS． |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |