| Objective To analyze the influential factors of bone mineral density (BMD) in postmenopausal women with type 2 diabetes (T2DM) and to revalue the influential factors for BMD. Methods 1) The clinical, biochemical, and special data of 416 postmenopausal women with T2DM were collected. Factor analysis was performed using SPSS 18.0. The common factors were extracted and the score of factors were calculated. 2) The patients were divided into 3 groups: the normal BMD, osteopenia, and osteoporosis group, according to BMD. The scores of factors were compared. Results 1) Three common factors were extracted from the original factors, representing BMI, insulin resistance factor, the aging and renal function factor, and the lipid metabolic factor, respectively. 2) The score of the three factors among three groups had significant difference. Conclusion Our research shows that main BMD- related factors in postmenopausal women with type 2 diabetes are BMI, insulin resistance factor, aging and renal function factor, and the lipid metabolic factor. |