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| 834 例女性 CTX-1、TRACP、BGP、BALP 水平与BMD相关性研究 |
| Study on the relevance of CTX-1，TRACP，BGP，BACP levels with BMD in 834 cases of female |
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| DOI： |
| 中文关键词: 骨代谢指标 骨股颈 骨密度 相关性 |
| 英文关键词:indicator of bone metabolism BMD relevance |
| 基金项目: |
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| 中文摘要: |
| 目的研究I型胶原C端肽（CTX-1 )、抗酒石酸酸性磷酸酶（TRACP)、骨钙素（BGP)、骨特异 性碱性磷酸酶（BALP)与股骨颈骨密度（BMD)的相关关系。方法采用美国Thermo公司酶标免疫分 析仪检测CTX-1、TRACP、BGP、BALP，采用美国Hologic公司生产的Discovery WA型骨密度仪检测股 骨颈BMD。将834例受试者检测结果按5岁为一年龄段分组，应用SPSSS 13. 0分析软件进行统计分 析。结果 35 ~45岁年龄段CTX-1、TRACP与BMD呈负相关，而BGP、BALP与BMD呈正相关；50 ~ 60岁年龄段BGP、BALP明显升高，CTX-1、TRACP、BGP、BALP均与BMD呈负相关；65岁以后BGP、 BALP开始下降，BGP、BALP与骨密度呈正相关，CTX-1、TRACP与骨密度呈负相关。结论 CTX-1、 TRACP、BGP、BALP是监测骨代谢水平及骨质疏松诊断、鉴别诊断的重要技术手段。 |
| 英文摘要: |
| Objective To study the relevance of CTX-1，TRACP，BGP，BALP with the neck BMD in female. Methods Enzyme immunoassay analyzer of Thermo company to detect CTX-1， TRACP， BGP， BALP， and BMD was measured by Discovery-WA-type bone mineral density detector of the United States Hologic company. To divide the results of 834 objects into several groups according to the standard of 5-year- old age as a group， SPSS 13.0 software was applicated for statistical analysis. Results The CTX-1， TRACP had negative relevance with BMD in 35 -45 age group and BGP， BALP had positive relevance with BMD in 35 -45 age group. The BGP， BALP increased significantly in 50 -60 age group， and CTX - 1、 TRACP、BGP、BALP had negative relevance with BMD in 50 -60 age group. BGP，BALPbegan to decline and had positive relevance with BMD after the age of 65，and CTX - 1，TRACP had negative relevance with BMD after the age of 65. Conclusion CTX-1，TRACP，BGP，BALP were the important technical means for monitoring the level of bone metabolism and the diagnosis and differential diagnosis of osteoporosis. |
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