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| 益肾健骨法对原发性骨质疏松症的临床研究 |
| Clinical research of the effect of invigorating the kidney and strengthening the bone method on primary osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2012.10.019 |
| 中文关键词: 骨质疏松 健骨丸 阿法骨化醇 骨密度 补肾 |
| 英文关键词:Primary osteoporosis Jiangu pill Alfacalcidol Bone mineral density Invigorating the kidney |
| 基金项目: |
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| 中文摘要: |
| 目的 了解近3年来就诊于江苏省中医院内分泌科患者骨质疏松、骨量减少发生情况，制定预防措施。验证中医益肾健骨法在治疗骨质疏松中的疗效。方法 通过对南京地区骨质疏松症及骨量减少的筛选，设定对照组（阿法骨化醇0.5μg,qd）、治疗组（阿法骨化醇0.5μg,qd+健骨丸5g,bid），观察患者临床表现，监测血钙、磷及骨密度两年。结果 治疗1年时，中药治疗组临床症状缓解明显；第二年时中药治疗组的跟骨骨密度增加明显优于对照组，血钙、血磷由于自身代谢及合理饮食改变不明显。结论 中药制剂健骨丸对骨质疏松有明显的疗效。 |
| 英文摘要: |
| Objective To investigate the incidence of osteoporosis and osteopenia in the patients who came to the Department of Endocrinology in Jiangsu Provincial Hospital in the past 3 years, to verify the effect of invigorating the kidney and strengthening the bone method on primary osteoporosis, and to formulate the prophylactic method. Methods Patients with osteoporosis and osteopenia in Nanjing area were screened and divided into 2 groups: the control group and the treatment group. Patients in control group were treated with 0.5 μg Alfacalcidol once a day. While patients in treatment group were treated with 0.5 μg Alfacalcidol once a day, and 5 g Jiangu pill twice a day. The clinical manifestations were observed. Bone mineral density (BMD) and the serum levels of calcium and phosphorus were examined for 2 years. Results After 1-year treatment, clinical symptoms of patients in the treatment group were relieved obviously. After 2-year treatment, the increase of BMD of the calcaneus in the treatment group was significantly higher than that in the control group. The serum levels of calcium and phosphorus did not show an obvious change due to self-metabolism and balanced diet. Conclusion The traditional Chinese medicine Jiangu pill has an obvious effect on primary osteoporosis. |
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