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| 定量CT测量的腹部脂肪分布与血脂和血糖的关系 |
| Relationships between abdominal visceral and subcutaneous fat measured by Quantitative CT with blood glucose and lipid |
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| DOI： |
| 中文关键词: 腹内脂肪；皮下脂肪；定量CT 代谢 |
| 英文关键词: |
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| 中文摘要: |
| 目的探讨腹部内脏脂肪面积（VFA )和皮下脂肪面积（SFA )与血脂、血糖代谢水平的关系。方法2010年于我院行腰椎定量CT( QCT )检查患者277名，年龄范围14耀90岁，中位年龄63岁。使用匝悦栽脂肪测量软件测量脐水平层面VFA和SFA;同时获得患者静脉血总胆固醇（TC )、甘油三酯 (栽郧）、高密度脂蛋白胆固醇（HDL-C)、低密度脂蛋白胆固醇（LDL-C )及空腹血糖（FBG )实验室检查 结果。为了使正常组和异常组年龄匹配，取年龄40岁及以上病例（246例），根据TC、TG、HDL-C、LDL-C,FBG结果的正常、异常，将VFA和SFA数据分组进行独立样本非参数检验。计算全部病例 (277例）正常、异常组VFA和SFA值的95%.可信区间，并做VFA和SFA与各项实验室指标的相关性 分析。结果 TC、TG、HDL-C、LDL-C正常、异常组间VFA值均有显著性差异（孕<0.05 )；TG正常、异 常组间SFA值有显著性意义（孕<0.05 )。VFA与TG、TC、FBG的相关性（则越0. 247 ,0. 326 ,0. 190 )大 于SFA(则越0.210，0. 151，0. 111 )。结论血脂代谢正常、异常人群腹部脂肪面积不同，异常人群大于 正常人群。VFA与血糖、血脂的相关性更大，其中TG为最明显相关因素。根据血糖、血脂异常组脂 肪面积的95%.可信区间可知，本组研究中，高血脂患者的VFA大于140.3 cm2，SFA大于187.2糟皂2 ；高血糖患者的VFA大于140.5 cm2。腹脂面积临界值的确定还有待做更大样本的测量。 |
| 英文摘要: |
| To explore the relationships hetween ahdominal visceral fat area ( VFA )， subcutaneous fat area ( SFA ) measured by quantitative CT( QCT ) and blood glucose and lipid. Methods Two hundreds and seventy-seven subjects were selected from the patients who underwent QCT exam of lumbar spine， aged 14-90 years，median age 63 years. VFA and SFA in umbilicus level were measured by the QCT soilware. The total cholesterol ( TC )， triglyceride ( TG )， high density lipoprotein cholesterol ( HDL- C )， iow-density lipoprotein cholesterol ( LDL-C ) and fasting blood glucose ( FBG ) of blood were obLained.According Lo TC，TG，HDL-C，LDL-C，FBG resulLs，246 subjecLs 為40 years old were classified as normal group and abnormal group， nonparameLric LesL was performed to determine the difference of VFA and SFA beLween groups. The 95%' confidence inLerval of all normal and abnormal group of VFA and SFA ( 277 cases ) were calculaLed. The Pearson correlation was performed between the VFA， SFA and laboratory parameLers. Results There were significant differences between TC， TG， HD L-C，LDL-C Lo normal and abnormal group of the VFA values (孕 < 0. 05 ). Significant difference was also found beLween TG Lo normal and abnormal group of Lhe SFA values ( P <0. 05 ). VFA and TG，TC，FBG correlation test ( r= 0. 247,0. 326,0. 190 ) is greaLer than the SFA ( r = 0. 210, 0. 151, 0. 111 ). Conclusion The normal and abnormal blood lipid meLabolism populaLions have different abdominal fat area. The correlation between VFA |
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