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| IL-17在绝经后骨质疏松方面的相关研究 |
| Study of the effect of IL-17 on postmenopausal osteoporosis |
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| DOI： |
| 中文关键词: 白介素-17(IL-17) 细胞因子；骨质疏松；绝经后 |
| 英文关键词:Interleukin-17 (IL-17) Cytokine Osteoporosis Postmenopausal |
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| 中文摘要: |
| 白介素-17(IL-17)，CD4*细胞亚群Thl7细胞分泌的特征性细胞因子，在抵抗胞外细菌、真菌 感染的宿主防御以及各种自身免疫性疾病发病中起到了重要作用。绝经后骨质疏松现被认为可能是 一种炎症过程，现有研究表明IL-17在绝经后骨质疏松的发病机制中具有重要作用。本文综述了近 几年IL-17在绝经后骨质疏松相关研究中的研究进展，为后续相关研究提供理论支撑。 |
| 英文摘要: |
| Interleukin-17 (IL-17) , which is the characteristic cytokine secreted by Thl7 cells of CD4 + cell subset, plays an important role in the process of host defense, such as resisting the extracellular bacterial and fungal infection and a variety of autoimmune diseases. Postmenopausal osteoporosis is now thought to be an inflammatory process. Studies have revealed that IL-17 plays an important role in the pathogenesis of postmenopausal osteoporosis. This paper reviews the research progress of the effect of IL-17 on postmenopausal osteoporosis in recent years, in order to provide theoretical support for the follow-up study. |
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