| Objective To investigate the feasibility and the advantage of comprehensive therapy, which composed of 3D CRT, hyperthermia, and anti-osteoporosis medicine, for cervical cancer in 100 patients, to improve clinical work and the quality of life of the patients, and to prevent and delay the occurrence of osteoporosis. Methods A total of 100 cervical cancer patients were divided into 2 groups (n=50, each). Patients in Group A were treated with three dimensional conformal radiotherapy, hyperthermia, and drug resistance of bone hydrophobic (A: R+H+OP), while patients in Group B were just treated with three-dimensional conformal radiotherapy (B: R). The adverse reactions of the treatment were observed. The efficacy was evaluated 1 month after the treatment. Results The level of BGP and BMD in Group A was significantly lower than that in Group B (P<0.01, P<0.001). The AKP level increased (P<0.05). No significant difference of calcium and phosphorus was observed between 2 groups (P>0.05). Conclusion Targeted selection of comprehensive therapy, including conformal radiotherapy, hyperthermia, and anti-osteoporosis medicine, can prevent and treat the bone destruction and secondary diseases caused by the tumor, which can relieve the symptoms and prevent the occurrence of serious complications. |