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| MicroRNA调控成骨分化与骨质疏松症相关性研究进展 |
| Research progress in micro RNA regulated osteogenic differentiation and osteoporosis |
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| DOI： |
| 中文关键词: MicroRNA ；骨髓间充质干细胞 成骨分化 信号通路 骨质疏松症 |
| 英文关键词:miRNA Bone marrow mesenchymal stem cells Osteogenic differentiation Signal pathway Osteoporosis |
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| 中文摘要: |
| 成骨分化抑制或减弱是骨质疏松症发病的重要因素之一，通过对骨代谢相关微小RNA( MicroRNA，miRNA)的深人研 究，发现其表达与成骨分化密切相关，本文通过对miRNA调控成骨分化的研究现状及其机制作详细阐述，旨在为骨质疏松症 的发病与诊疗提供一定的理论依据。 |
| 英文摘要: |
| The inhibition or weakening of osteogenic differentiation is one of the important factors of osteoporosis. The in-depth researches of bone metabolism^elated microRNA (miRNA) reveal a close relationship between the expression of miRNA and osteogenic differentiation. This paper elaborates the research status of osteogenic differentiation regulated by miRNA and its mechanisms，aiming at providing a theoretical basis for the pathogenesis and treatment of osteoporosis |
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