|
MicroRNA调控成骨分化与骨质疏松症相关性研究进展 |
Research progress in micro RNA regulated osteogenic differentiation and osteoporosis |
|
DOI: |
中文关键词: MicroRNA ;骨髓间充质干细胞 成骨分化 信号通路 骨质疏松症 |
英文关键词:miRNA Bone marrow mesenchymal stem cells Osteogenic differentiation Signal pathway Osteoporosis |
基金项目: |
|
摘要点击次数: 1027 |
全文下载次数: 1522 |
中文摘要: |
成骨分化抑制或减弱是骨质疏松症发病的重要因素之一,通过对骨代谢相关微小RNA( MicroRNA,miRNA)的深人研 究,发现其表达与成骨分化密切相关,本文通过对miRNA调控成骨分化的研究现状及其机制作详细阐述,旨在为骨质疏松症 的发病与诊疗提供一定的理论依据。 |
英文摘要: |
The inhibition or weakening of osteogenic differentiation is one of the important factors of osteoporosis. The in-depth researches of bone metabolism^elated microRNA (miRNA) reveal a close relationship between the expression of miRNA and osteogenic differentiation. This paper elaborates the research status of osteogenic differentiation regulated by miRNA and its mechanisms,aiming at providing a theoretical basis for the pathogenesis and treatment of osteoporosis |
查看全文 查看/发表评论 下载PDF阅读器 |
关闭 |