| Objective To investigate the relationship between low remodelling osteoporosis and the spinal degenerative diseases，and to explore the damage of osteoporosis on the spine degeneration in the elderly patients. Methods The bone mineral density (BMD) was detected using dual-energy X-ray absorptiometry. The clinical observation and the collection of the imaging data were performed. The large-sample random sampling was also performed. A SPSS 13. 0 statistical software was used to analyze all the data of 505 patients over 50 years old in a year. The data of the spinal diseases with low remodelling osteoporosis were collected. Results The comparison of BMD of different lumbar vertebrae in each group was performed using single factor analysis of variance. The enumeration data were analyzed using Spearman rank correlation analysis. The correlation between osteoporosis and diseases such as the lumbar instability was analyzed using non~conditional logistic regression analysis. The results revealed that the partial regression coefficient of the thoraco-lumbar fracture was 1. 026 (P =0. 021，OR 2. 789). The partial regression coefficient of the spinal degeneration was 0. 225 (P= 0. 035，OR 2. 253). The partial regression coefficient of the lumbar instability was 0. 828 (P =0. 004，OR 2. 289). The partial regression coefficient of the spondylolisthesis was 0. 782 (P =0. 024，OR 2. 185). The partial regression coefficient of the cervical spondylosis was 0. 691 (P =0. 045，OR 1.211). The partial regression coefficient of the spinal stenosis was 0. 972 (P = 0. 031，OR 2. 57). The partial regression coefficient of the spinal deformity was 0. 972 (P =0. 025，OR was1.002).The partial regression coefficient of age was 0.48(P=0.000,OR 1.049).The partial regression coefficient of genden was -1.035 (P =0.000，OR 0.355). Osteoporosis and the spinal degenerative diseases. including the spinal degeneration, the spinal instability, the thoraco-lumbar fractures, the spinal stenosis, the spinal deformity, the cervical spondylosis, and the spondylolisthesis，were correlated with the increase of age. Conclusion Along with the increase of age，the incindence of low remodeling osteoporosis increases. Bone loss and osteoporosis can both accelerate the spinal degeneration. Osteoporosis can also accelerate the spinal degenerative diseases, such as the spinal degeneration, the spinal instability, the thoraco-lumbar fractures，the spinal stenosis，the spinal deformity，the cervical spondylosis，and the spondylolisthesis. |