| The long-term excessive drinking can lead to a series of changes in the body, is unfavorable for bone health. Alcohol is bad for the adult skeletal, to inhibit bone formation, increased bone resorption. Alcohol for the growth of bone is bad, can affect the peak bone mass, increase the prevalence of osteoporosis. The effects of alcohol on bone mainly through alcohol for the role of nutrition, hormone, sex hormone, bone cells, intracellular signal pump system affects bone health. Specific performance in alcohol induced hypomagnesemia, hypocalcemia, hyperphosphatemia, active vitamin D level decreased； alcohol makes calcitonin levels in blood increased, decreased or increased levels of parathyroid hormone, cortisol level increased; alcohol can make testosterone and estrogen decrease; alcohol makes the activity of osteoblasts injury, the activity of osteoclasts normal; alcohol directly intervene in the type 1 insulin-like growth factor receptor (IGF-IR) and the effect of bone formation. Therefore, the typical characteristics of alcoholic bone is impaired bone formation and bone resorption relative to normal. |