肝肾阴虚型骨质疏松症综合疗效评价新方法——多指标权重系数法
A new method to evaluate the efficacy of the treatment of osteoporosis with the liver and kidney Yin deficiency: a method of index weight coefficient
投稿时间:2013-08-30  
DOI:
中文关键词:  肝肾阴虚  综合疗效  评价指标  骨质疏松症  权重系数
英文关键词:The liver and the kidney Yin deficiency  Comprehensive curative effect  Index of evaluation  Osteoporosis  Weight coefficient
基金项目:
作者单位E-mail
邵敏 广州中医药大学附属骨伤科医院广州 510240  
汪钦生  wqs370@163.com 
曾振明   
摘要点击次数: 866
全文下载次数: 0
中文摘要:
      目的:观察肝肾阴虚型骨质疏松症患者治疗前后各指标的变化,运用各指标的权重系数对其中期疗效进行综合评价,探讨一种新的评价方法。方法通过文献检索及临床观察,纳入60例肝肾阴虚型骨质疏松症患者,补益肝肾治疗加基础钙剂。采用专家调查形式对各指标进行权重系数划定,观察治疗前、治疗5个月后疼痛和中医主要症状、体征评分,骨代谢生化指标(β-CrossLaps、P1NP)、骨密度指标的检测值,从而确定疗效等级,评价其5个月后的疗效以及各指标前后的变化。结果各指标的权重系数分别为:疼痛28%、中医症状体征28%、P1NP15.3%、β-CrossLaps6.7%、L2-L4椎体BMD22%。其中以综合权重评分分值>23.8%为治愈,13.4%~23.8%为好转,<13.4%为未愈,各指标治疗前后均有变化。结论对于一种多指标评价体系,可以运用权重系数方法进行综合评价,值得临床推广。
英文摘要:
      Objective To observe the changes of indicators in patients with the liver and the kidney Yin deficiency osteoporosis before and after the treatment, and to investigate a new evaluation method by using the weight coefficient of each index to comprehensively evaluate the curative effect.Methods By literature retrieval and clinical observation, 60 patients with the liver and the kidney Yin deficiency osteoporosis were selected.All the patients were given the tonifying the liver and the kidney treatment with calcium supplements.Each index weight coefficient was defined according to expert survey form.Pain, main symptoms and signs according to traditional Chinese medicine, bone metabolic biochemical index (β-CrossLaps and P1NP), and bone mineral density ( BMD) were determined before and 5 months after the treatment, in order to determine the grade of the curative effect.The changes of the indexes before and 5 months after treatment were also evaluated.Results The weight coefficient of pain, symptoms and signs according to traditional Chinese medicine, P1NP, β-CrossLaps, BMD of L2-L4 was 28%, 28%, 15.3%, 6.7%, and 22%, respectively.The comprehensive weighted score over 23.8% was considered as cured, 13.4% -23.8% was considered as improved, and below 13.4%was considered as non-cured.Various indicators changed before and after the treatment. Conclusion As a multi-index evaluation system, using the weight coefficient method can make a comprehensive evaluation, which is worthy of clinical promotion.
查看全文  查看/发表评论  下载PDF阅读器
关闭
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=75386E6AC000F55D23ADCE1C30EBD1C7E0C478D5BB9091503D88A2C0236D879D748802EF94223593471B63589DE0274BF7FF4ED4603FE2794442A763833B88FA2761E963D526D49A352B59C85BCDC62E54A4EC5D45431A29141520FD6F6956CE721DE55C365979BFE141660860A62C1681F2BBE86B20420E2E85117F7DC93F9815315A3C34142D38756C57316AC037570C52B3B22C238762&pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=527A01A248DACB72&jid=CA678592D11E309E8E3FB3B2BFE9BE1A&yid=9EAD63ADE6B277ED&aid=187DB8D3FE6674281AB86950FEBCD418&vid=&iid=5D311CA918CA9A03&sid=8587C7CAA7A3D0DB&eid=073C3CF5F13F64FE&fileno=201408015&flag=1&is_more=0"> var my_pcid="A9DB1C13C87CE289EA38239A9433C9DC"; var my_cid="527A01A248DACB72"; var my_jid="CA678592D11E309E8E3FB3B2BFE9BE1A"; var my_yid="9EAD63ADE6B277ED"; var my_aid="187DB8D3FE6674281AB86950FEBCD418";