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| 女性Graves病患者血清Ghrelin与骨密度的关系 |
| Relationship between serum ghrelin and bone mineral density in women with Graves disease |
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| DOI： |
| 中文关键词: Graves病 女性 骨密度 Ghrelin |
| 英文关键词:Graves disease Female Bone mineral density Ghrelin |
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| 中文摘要: |
| 目的研究女性Graves病患者血清Ghrelin与骨密度（BMD)的关系。方法80例女性Graves病患者，合并骨质疏松 (OP)组38例（OPl组）、骨含量正常组42例（OP2组），健康女性对照组25例（N组），测血清Ghrelin、FT3、FT4、TSH，并测量腰 椎和股骨BMD。结果（1) OPl、OP2组与N组比较，Ghrelin的水平差异有统计学意义（P <0.05);(2) OPl、OP2组Ghrelin水 平无明显差异(P >0.05);(3) OPl、OP2组中Ghrelin与股骨BMD、椎骨BMD均无关(P >0.05)。结论合并OP患者血液中 Ghrelin水平与股骨BMD、椎骨BMD间无相关性。 |
| 英文摘要: |
| Objective To investigate the relationship between serum ghrelin level and bone mineral density (BMD) in woman with Graves disease. Methods Eighty female patients with Graves disease were divided into group OP1 (38 cases， with osteoporosis) and group OP2 ( 42 cases， without osteoporosis) . Twenty4five healthy female people without Graves disease and osteoporosis were chosen as control group (group N). The serum levels of ghrelin，FT3，FT4，and TSH in all groups were detected. BMD of the lumbar vertebrae and the femur was determined using dual-energy X-ray absorptiometry. The correlation between ghrelin and BMD was analyzed. Result The serum levels ghrelin in group OP1 and group OP2 were significantly different with those in group N (P < 0. 05). But no difference of the serum levels of ghrelin between group OP1 and group OP2 was observed (P >0.05). The serum ghrelin level in group OP1 and group OP2 showed no correlation with BMD of the lumbar vertebrae and the femur (P > 0. 05). Conclusion The serum ghrelin level in woman with Graves disease is not correlated with BMD of the lumbar vertebrae and the femur. |
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