| Objective To investigate the relation between coronary heart disease (CHD) and low bone mineral density（BMD, including osteoporosis and osteopenia）in the elderly. Methods A retrospective analysis of 130 elderly CHD patients diagnosed by coronary angiography was conducted in our hospital. According to the results, the patients were divided into CHD group and non-CHD group. In addition, the patients were divided into osteoporosis group, osteopenia group and the normal group based on BMD results by dual-energy X-ray absorptiometry. Difference of the incidence of CHD among the 3 groups was compared. The relationship between low BMD and CHD was further analyzed. Results 1) There were significant differences in age, hypertension, smoking, diabetes, statins, serum creatinine, and high-density lipoprotein cholesterol<40mg/dl between CHD and non-CHD group (P<0.01).There were no statistically significance between the two groups in the body mass index (BMI), gender, family history of CHD, drugs affected BMD (calcium, steroids and bisphosphonates), low-density lipoprotein cholesterol>130mg/dl, and levels of serum calcium. 2) The incidence of CHD in the osteopenia group and osteoporosis group was significantly higher than that in normal group, and the difference was statistically significant among the 3 groups (P<0.01). 3) Compared with the traditional risk factors of CHD, the relative risks of low BMD, diabetes, hypertension were 20.1, 3.12, and 4.85, respectively. Conclusion The incidence of CHD in the low BMD groups is higher than that in normal group. There is a certain correlation between incidence of CHD and low BMD. |