微量元素锶与骨质疏松症
Trace element strontium and osteoporosis
  
DOI:10.3969/j.issn.1006-7108.2014.10.027
中文关键词:  骨质疏松症    骨形成  骨吸收  骨折
英文关键词:Osteoporosis  Strontium  Bone formation  Bone resorption  Fracture
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作者单位
王买全1 李运峰2* 1. 河南省人民医院郑州450000 2. 四川大学华西口腔医学院成都610041 
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中文摘要:
      随着世界范围内老龄人口的不断增加,骨质疏松症已经成为严重危害中老年人健康的常见病、多发病。骨质疏松症患者不仅易于发生骨折,他们在接受牙种植、人工关节置换等治疗时,还经常存在生物植入材料骨整合不佳、甚至松动脱落的问题,严重限制了中老年患者生活质量的提高。因此,探索各种科学、合理的方法改善骨质疏松症患者的骨代谢状况,预防骨质疏松性骨折的发生,促进骨质疏松性骨折的愈合,改善骨质疏松状态下植入体的骨整合已经成为骨科、矫形外科、口腔颌面外科以及老年医学等多学科领域内亟待解决的难题。近期的研究发现,微量元素锶是一种具有促进成骨和抑制骨吸收双重作用的抗骨质疏松药物,本文就微量元素锶治疗骨质疏松症的研究进展作一综述。
英文摘要:
      With the increase of aging population worldwide, osteoporosis has become a common disease seriously damaging health in the elderly. People with osteoporosis not only prone to fractures, but also confront the failure of dental implants and artificial joint replacement. These severely limit the improvement of the quality of life of the elder patients. Therefore, to explore a scientific way to improve bone metabolism in patients with osteoporosis, to prevent from osteoporotic fractures, and to promote fracture healing has become an urgent problem in orthopedics, orthopedic surgery, oral and maxillofacial surgery, and multidisciplinary field of geriatrics. Recent studies have found that trace element strontium is a drug that has dual effects of both promoting osteogenesis and inhibiting bone resorption. This paper reviews progress on the study of trace element strontium for the osteoporosis treatment.
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