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| 认知功能障碍评估对老年骨质疏松症患者临床治疗影响研究分析 |
| The effect of assessment to cognitive dysfunction on the clinical treatment of senile osteoporosis |
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| DOI：10.3969/j.issn.1006.7108.2014.11.015 |
| 中文关键词: 骨质疏松症 认知功能障碍 骨密度T值；脉冲电磁场 |
| 英文关键词:Osteoporosis Cognitive dysfunction Bone mineral density Pulse electromagnetic field |
| 基金项目:三峡大学第一临床医学院科研发展基金项目（KFJ2011046) |
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| 中文摘要: |
| 目的 对比抗骨质疏松症药物治疗（Anti osteoporosis drug therapy，AODT)与药物联合脉冲电磁场（Drug and Pulse Electromagnetic Field，DPEF)治疗对老年骨质疏松症伴认知功能障碍患者影响的随访调查研究。方法 应用回顾性研究对照方法，随机选取2011年3月-2013年12月来我院康复医学科就诊的60名老年骨质疏松症患者。随机选择并将纳人研究的患者分为AODT组(30人）和DPEF组（30人）。所有患者都有一定程度的认知障碍，但是在入院治疗前都有步行能力。AODT组患者应用抗骨质疏松症药物治疗，DPEF组应用抗骨质疏松症药物联合脉冲电场治疗。在治疗前及治疗后第3个月， 第6个月及第12个月分别对患者进行康复评定及腰椎骨密度检测。评估内容包括简易精神状况问卷调查表（SPMSQ量表）评分，功能独立性评分(Function Independent Measure，FIM)，腰椎骨密度T值（Bone mineral density T score)及生活质量评分 (EQ-5D)。结果 随访12个月后发现，AODT组患者与DPEF组患者生活质量（EQ-5D)评分及腰椎骨密度T值明显提高（P >0.05)。DPEF组患者功能独立性评分明显高于AODT组患者，差异有统计学意义。两组患者复发率对比无差异(P > 0.05)。结论 DPEF治疗技术与AODT治疗技术相比，可以有效提高老年骨质疏松症伴认知功能障碍患者的生活质量及功能独立能力，有效提高腰椎骨密度。 |
| 英文摘要: |
| Objective To compare the treatment between anti osteoporosis drug therapy (AODT) and anti osteoporosis drug therapy associated with drug pulse electromagnetic fields (DPEF) in senile osteoporosis. Methods Using retrospective study with control method，60 senile osteoporosis patients in rehabilitation medicine clinic of our hospital were randomly selected from March 2011 to December 2013. The patients selected were divided into AODT group (30 cases) and DPEF group (30 cases). All patients were with a certain degree of cognitive impairment but with the ability to walk before the treatment. Anti-osteoporosis drug treatment was used in the AODT group and anti-osteoporosis drug combined pulse electric field was used in the DPEF group. The DPEF rehabilitation evaluation was carried out in the 3，6，and 12 months for the patients，respectively. The evaluation included SPMSQ score，functional independence score (FIM)，bone mineral density T score of the lumbar vertebra，and quality of life score (EQ- 5D). Results EQ-5D and bone mineral density T score of the lumbar vertebra increased significantly in both AODT group and DPEF group (P >0. 05) in 12 months of followed up. FIM in the DPEF group was obviously higher than that in AODT group and the difference was statistically significant (P <0.05). The recurrence in the two groups was no different (P > 0. 05). Conclusion The quality of life，functional independence ability and bone mineral density of the lumbar vertebra effectively improve with the treatment of DPEF compared with the treatment of AODT. |
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