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| 特发性尿钙增多症合并骨质疏松1例并文献分析 |
| Analysis of a case of idiopathic hypercalciuria combined with osteoporosis，and a literature review |
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| DOI：10.3969/j.issn.1006.7108.2014.11.019 |
| 中文关键词: 特发性尿钙增多症 骨质疏松 |
| 英文关键词:Idiopathic hypercalciuria Osteoporosis |
| 基金项目:2011年国家临床重点专科建设项目 |
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| 中文摘要: |
| 特发性尿钙增多症(idiopathic hypercalciuria，IH)的概念由Albright[1]等人于1953年提出，指在正常钙摄入的情况下，排除各种继发因素，血钙正常，24小时尿钙>4 mg/kg(0. 1 mmol/kg)及尿Ca/ Cr >0.21即可诊断的一种疾病。临床上IH并不少见，有报道成人尿石症伴IH者达40% ~60%，而小儿尿石症中仅2% ~5%是由IH所致。但IH合并严重骨质疏松者少有报道，现将我院内分泌科1例IH合并骨质疏松报道如下。 |
| 英文摘要: |
| Idiopathic hypercalciuria (IH) is a heterogenous disorder first described by Albright et al in 1953. It is characterized by normal blood calcium (Ca) but excretion urinary Ca >4 mg/kg in 24 hours (normal 0. 1 mmol/kg) and urine Ca/Cr >0. 21 under normal Ca uptake and no secondary factors. IH is not few in the clinic. It is reported that in adults 40%~- 60% of urolithiasis are associated with IH，while in children only 2%~5% of urolithiasis are associated with IH. However，serious osteoporosis associated with IH is seldom reported. We report a case of IH combined with osteoporosis in the Department of Endocrinology of our hospital. |
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