内蒙古西部地区蒙古族骨质疏松症的发病及其危险因素分析
The incidence and risk factors of osteoporosis in Mongolians of west Inner Mongolia region
投稿时间:2014-04-30  
DOI:
中文关键词:  骨质疏松症  蒙古族  危险因素
英文关键词:Osteoporosis  Mongolian  Risk factors
基金项目:内蒙古自治区自然科学基金项目(2012MS1130)
作者单位E-mail
田静 内蒙古医科大学附属医院呼和浩特 010050  
仝林虎  tlh201010@163.com 
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中文摘要:
      目的:探讨内蒙古西部地区蒙古族骨质疏松症( OP)的发病及其危险因素,以便针对性地进行干预。方法连续抽取内蒙古医科大学附属医院体检中心300名蒙古族健康人群进行OP患病率调查,发现OP 43例,为病例组,未发生OP的257名中随机抽取86名为对照组。对2组的年龄、身高、体重指数和性别等17项予以比较分析。所得资料在单因素分析的基础上,又做多因素logistic回归。结果 OP的患病率为14.33%。 OP发生的相关因素分析,排除进入模型的其他作用因素后,年龄每增加1岁和体重指数每增加1个单位,促使OP发生的危险性分别是原来的1.10倍和1.21倍( OR分别是1.10和1.21,其95%可信区间内均不包含1, P均<0.05);城市居住和进食蔬菜少促使发生OP的危险性分别是农牧区居住和进食蔬菜多的3.85倍和3.82倍(OR分别是3.85和3.82,其95%可信区间内均不包含1, P均<0.05),促进发病。而男性和饮酒多促使发生OP的危险性分别是女性和饮酒少或无的0.41倍和0.11倍( OR分别是0.41和0.11,其95%可信区间内均不包含1, P均<0.05),女性更易发生OP,饮酒多可阻止发病。结论增龄、体重指数增高、城市居住、进食蔬菜少和女性是发生OP的危险因素,而饮酒多为其保护因素。
英文摘要:
      Objective To explore the incidence and the risk factors of osteoporosis ( OP) in Mongolians of west Inner Mongolia region, so as to get targeted intervention.Methods Three hundred Mongolian healthy people were continuously extracted from the health examination center of the Affiliated Hospital of Inner Mongolia Medical University.Forty-three cases were diagnosed of OP. They were in the case group.Eighty-six cases were randomly selected from 257 non-OP people as control group.Seventeen indexes including age, height, and body mass index were compared between the two groups.Single factor analysis and multi-factor logistic regression were conducted.Results The prevalence of OP was 14.33%.The analysis of OP-related factors showed that after excluding other roles into the model, every 1-year increase of age and every 1-unit increase of body mass index increased the OP risk by 1.10 and 1.21 times, respectively (OR 1.10 and 1.10, 95%confidence interval not containing 1, P<0.05).Urban living and less intake of vegetables increased the OP risk by 3.85 and 3.82 times more than farm living and more intake of vegetables ( OR 3.85 and 3.85, the 95%confidence interval not containing 1, P<0.05).Male gender with more drinking increased the OP risk comparing to females and less drinking (OR 0.41 and 0.11, the 95% confidence interval not containing 1, P<0.05).Females were more vulnerable to OP.Drinking in women prevented the occurrence of the disease.Conclusion Age, body mass index increase, urban residential, less vegetable intake, and female gender are OP risk factors.More drinking is the protective factor.
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