密云地区腰椎定量CT骨密度测量分析
Quantitative CT analysis of bone mineral density of the lumbar vertebra in Miyun
  
DOI:10.3969/j.issn.1006-7108.2015.02.011
中文关键词:  骨密度  骨质疏松  定量CT  腰椎
英文关键词:Bone mineral density  Osteoporosis  Quantitative CT  Lumbar vertebra
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王素琴 陈静 曹宝卿 李鹏 郭美玲 杨鸿兵* 北京市密云县中医医院北京 101500 
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中文摘要:
      目的 探讨腰椎QCT骨密度测量的峰值骨量,骨量丢失,骨质疏松症发病率, 为临床诊断和治疗提供依据。方法 整理在本院进行腰椎QCT骨密度测量的患者222例。其中:男性97例,年龄30~87岁,平均63.3岁;女性125例,年龄23~87岁,平均63.1岁。按照世界卫生组织提出新的年龄分段方法,分为3组:青年组<44岁、45<中年组<59岁、老年组>60岁。利用SPSS19.0对数据进行处理,计量资料采用 方式表示,偏相关分析、线性回归分析、独立样本T检验、多因素方差分析检验,P<0.05表示差异有显著性,计数资料采用卡方检验。结果 男女性峰值骨量出现于青年组,女性峰值高于男性;中年后骨量开始丢失,老年后女性较男性丢失明显(P<0.05);女性骨质疏松症发病率高于男性。结论 QCT腰椎骨密度测量精准、简便、快捷具有广泛的临床应用价值;对人体骨量的变化,诊断、预防骨质疏松症;预测骨质疏松性骨折起着重要作用
英文摘要:
      Objective To investigate the peak bone mass, bone mass loss, and osteoporosis incidence by the measurement of bone mineral density of the lumbar vertebrae using QCT, and to provide the evidence for clinical diagnosis and treatment. Methods Two hundred and twenty-two cases of lumbar bone mineral density measurement using QCT in the hospital were collected. There were 97 males, aging from 30 to 87 years old and 63.3 years in average, and 125 females, aging from 23 to 87 years old and 63.1 years in average. According to the WHO new age segmentation method, they were divided into 3 groups: young group (< 44 years), middle-aged group (from 45 to 59 years old), elder group (above 60 years old). The data were processed using a SPSS19.0 software. The measurement data were presented as . They were analyzed using partial autocorrelations, linear regression, independent samples T test, and multi factor analysis of variance test. P < 0.05 indicated that there was a significant difference. Counting data were analyzed using chi square test. Results The peak bone mass appeared in young group and it was higher in females than in males. Bone mass loss occurred from middle age, and it was more obvious in elderly women than in men (P<0.05). The incidence of osteoporosis was higher in females than in men. Conclusion The bone mineral density measurement of the lumbar vertebrae using QCT is precise, simple, fast, and is of wide clinical application value. It plays an important role in observation of human bone mass, diagnosis and prevention of osteoporosis; and prediction of osteoporotic fracture.
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