| Objective To investigate the influence of body composition on bone mineral density of male patients with type 2 diabetes using dual energy X-ray absorptiometry (DXA). Methods One hundred and seven 50-60-year-old male patients with type 2 diabetes in our hospital were selected and divided to normal weight group, overweight group, and obese group. Height and body weight were measured and body mass index (BMI) was calculated. Blood glucose and lipid were determined using a automatic biochemical analyzer. Glycosylated hemoglobin (HbA1c) was measured using a high pressure liquid chromatography. Bone mineral density (BMD) of the lumbar spine and left femoral trochanter, and body composition were measured and statistically analyzed using dual energy X-ray absorptiometry. Results BMD of the lumbar vertebrae in 3 groups was 1.12±0.05, 1.21±0.07, and 1.36±0.09, respectively. BMD of the left femoral greater trochanter was 1.12±0.06, 1.22±0.08, and 1.41±0.08, respectively. The muscle mass of various parts of the body was positively correlated with BMD, and the thigh was greater than the upper limb and the upper limb was greater than the trunk. Effect of fat content on BMD was different in different parts of the body. The fat of the upper limb and thigh was positively correlated with BMD, but the fat of trunk was negatively correlated with BMD. Age, glycosylated hemoglobin, and blood lipids had no effect on BMD in male patients with type 2 diabetes. However, BMI, muscle mass, and fat content had significant effect on BMD. Conclusion BMI, muscle mass, and fat content have a direct impact on BMD in male patients with type 2 diabetes. Male patients with type 2 diabetes should do exercise, reduce abdominal fat content, and increase the content of the limb muscles to prevent the occurrence of osteoporosis. |