| Objective To investigate the effect of alcohol drinking on bone mineral density (BMD) in middle-aged males with type 2 diabetes. Methods Ninety middle-aged males with type 2 diabetes were selected and divided into 2 groups, alcohol drinkers (n=45) and non-alcohol drinkers (n=45). In alcohol drinking group, they were divided to 3 levels, little amount (<50g/d), middle amount (50-100g/d), and large amount (>100g/d), according to their alcohol consumption. And according to the alcohol drinking time, they were divided to <10 years, 10-20 years, and >20years levels. BMD of the femoral neck, the greater trochanter, and the lumbar spine was measured using dual energy X-ray absorptiometry. The relationship between the different alcohol consumption, the different alcohol drinking time, and BMD of the different sites was analyzed. Results Compared to non-alcohol drinking group, BMD of the femoral neck, the greater trochanter, and the lumbar spine was significantly lower than that in alcohol drinking group with alcohol consumption 50-100 g/d and >100 g/d, and with alcohol drinking period 10-20 years and >20 years (P<0.01). Alcohol consumption >50 g/d and alcohol drinking period >10 years were negatively correlated with BMD of the femoral neck, the greater trochanter, and the lumbar spine (P<0.01). Conclusion BMD in the middle-aged males with type 2 diabetes, whose alcohol consumption >50 g/d and alcohol drinking period >10 years, decreases significantly. The incidence of osteoporosis increases. |