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| Rspo1通过Wnt/β-catenin信号通路调节成骨细胞分化的研究进展 |
| Research progress of Rspol regulation of osteoblast differentiation through the Wnt/β-catenin pathway |
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| DOI：10.3969/j.issn.1006.7108.2015.04.025 |
| 中文关键词: Rspo1 Wnt/β-catenin信号通路 成骨细胞 |
| 英文关键词:Rspo1 Wnt/β-catenin pathway Osteoblast |
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| 中文摘要: |
| 在成骨细胞的分化增殖中，经典Wnt /β-catenin通路起着重要的调节作用;此通路中的任何一个因子都能影响成骨细胞的分化增殖。近几年里,大量研究证明R-脊椎蛋白家族巳成为Wnt/β-catenin信号通路的重要调节因子。本文就Rspo1通过Wnt/β-catenin信号通路调控影响成骨细胞分化增殖的研究进展作一综述。 |
| 英文摘要: |
| The classic Wnt/β-catenin pathway plays a crucial role in the differentiation and proliferation of osteoblasts. Any factor in the pathway can affect the proliferation and differentiation of osteoblasts. In recent years, a large number of studies show that R- spondins (RSPOs) is an important regulating factor in Wnt/β-catenin signaling pathway. This paper reviews the progress in Rspo1 regulation of osteoblast differentiation through Wnt/β-catenin signaling pathway. |
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