山西地区2012年至2013年我院就诊人群血清维生素D水平状况调查
The investigation of vitamin D status in patients in Shanxi from 2012 to 2013
  
DOI:10.3969/j.issn.1006-7108.2015.06.014
中文关键词:  25(OH)D  甲状旁腺激素  山西省
英文关键词:25-hydroxyvitamin D  Parathyroid hormone  Shanxi province
基金项目:
作者单位
邓捷1 朱亦堃2* 李志刚3 李兴2 郭存久3 郑晓宾4 1. 山西省长治市城区第二人民医院山西长治 046011 2. 山西医科大学第二医院内分泌科太原030001 3. 山西医科大学第二医院检验科太原030001 4. 山西省长治医学院附属和济医院山西长治 046000 
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中文摘要:
      目的 探讨目前山西地区不同季节人群的维生素D状况。方法 通过对2012 年6 月至2013年7月山西医科大学第二医院就诊的1313例患者血清25 羟维生素D [ 25(OH)D] 和甲状旁腺激素(PTH)水平,应用电化学发光免疫法测定血清25-羟维生素D[25(OH)D]、甲状旁腺激素(PTH),按不同季节、性别进行分析。结果 ①所有检测人员的血清25(OH)D平均水平: 男性(11.38±6.29)ng/mL,女性(9.04±5.71)ng/mL。按照IOF维生素D水平判定标准:严重缺乏者占62.2%;维生素D缺乏者占28.46%;维生素D不足者占6.1%;维生素D充足者占3.25%。②血清25(OH)D水平与季节有显著相关性(r=0.228,P<0.05);③血清25(OH)D与PTH 呈负相关(r=-0.272,P<0.05)。结论 受各种因素影响,目前山西地区成年人群中存在严重的维生素D不足和缺乏状况,应受到广泛的关注并改善现状,降低维生素D相关疾病的发病率。
英文摘要:
      Objective To analyze the current vitamin D status in the population of Shanxi in different seasons. Methods Serum 25 (OH) D and PTH levels of 1313 patients in the Second Hospital of Shanxi Medical University were analyzed from June 2012 to July 2013. They were detected using electrochemical luminescence immune method. The date were analyzed according to different season and gender .Results 1) The average level of serum 25 (OH) D in men and women was 11.38±6.29 ng/ml and 9.04±5.71 ng/ml, respectively. According to the IOF criteria of vitamin D, the ratio of serious deficiency, deficiency, insufficiency, and sufficiency was 62.2%, 28.4%, 6.1%, and 3.25%, respectively. 2) There was significant correlation between the levels of serum 25 (OH) D and the season (r=0.228, P<0.05). 3) There was negative correlation between PTH and the level of serum 25(OH) D (r= -0.272, P<0.05). Conclusion Vitamin D insufficiency and deficiency exist in the adult population in Shanxi due to various factors. It should be paid widely attention and improved. More efforts should be done to reduce the incidence of vitamin D associated diseases.
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