| Objective To investigate the bone mineral density and its influential factors in patients with gestational diabetes mellitus (GDM). Methods Pregnant women who checked or hospitalized in Xiaogan Central Hospital from September 2011 to March 2013 were enrolled. One hundred and sixty normal pregnant women were as control group, and 156 cases of pregnant women with GDM were in GDM group. Bone mineral density of the right calcaneum was measured using ultrasonic bone density detector. Fasting blood sugar (FBS) and glycosylated hemoglobin (HbA1C) were detected and statistical analysis was performed. Results In GDM group, the bone density detection results of BUA, SOS, and SI were significantly lower than those in the control group (P<0.05). In GDM group, the percentage of osteopenia and osteoporosis was 15.38% and 5.13%, respectively, which was significantly higher than that in the control group (P<0.05). Pearson correlation analysis showed that SI was negatively correlated with age, gestational age, FBS, and HbA1C (r=-0.160, -0.265, -0.160, and -0.156, P<0.05), but positively correlated with BMI (r=0.069, P<0.05). Conclusion The incidence of osteopenia and osteoporosis in patients with GDM is significantly higher than that in normal pregnant women, and SI of the bone mineral density of the calcaneus is negatively correlated with age, gestational weeks, FBS, and HbA1C, but positively correlated with BMI. |