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| TBS在监测及诊断骨质疏松方面的应用价值 |
| The use of TBS in the monitor and diagnose of osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2015.06.026 |
| 中文关键词: 骨小梁分数 骨质疏松 骨密度 骨微结构 |
| 英文关键词:Trabecular bone score Osteoporosis Bone mineral density Bone microarchitecture |
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| 中文摘要: |
| 利用DXA（dual energy X-ray absorptiometry，双能X线吸收法）测得的单位面积骨密度值（areal bone mineral density，BMD）是诊断骨质疏松的金标准。骨质疏松患者骨量减少的同时通常存在骨微结构的退化，表现为骨小梁数量减少、间距增加以及骨小梁间连接性下降，而BMD仅能显示骨量的变化，不能提供关于骨结构的信息。因此，仅靠BMD来诊断或排除骨质疏松是不全面的。骨小梁分数（trabecular bone score，TBS）是一种可由DXA图像获得的反映图像上灰阶变化的结构参数，能有效评估骨的微结构、描述骨的质量。本文将从TBS的检测方法、与其他检测骨折风险指标之间的关系以及TBS的有效性和不足等方面来介绍TBS在监测及诊断骨质疏松方面的应用价值。 |
| 英文摘要: |
| Areal bone mineral density (BMD) measured with dual energy X-ray absorptiometry (DXA) is the gold standard for the diagnosis of osteoporosis. An osteoporotic patient who has low bone mass usually has degenerated microarchitecture, including the decrease of trabecular number, the increase of space between trabecular bone, and decreased connection between the trabeculae. BMD is only an assessment of bone mass. It does not provide information of bone microarchitecture. Therefore, relying on BMD to diagnose or to exclude osteoporosis is not comprehensive. Trabecular bone score (TBS) is a texture parameter that evaluates pixel gray-level variation in DXA images of the lumbar spine. TBS can assess bone microarchitecture and describe the quality of bone. This paper introduces the ability of TBS to monitor and to diagnose osteoporosis from the aspects of TBS detection method, the relationship with other bone fracture risk detection methods, and the efficacy and shortcome of TBS. |
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