不同工作环境下煤矿矿工骨质疏松症的对照研究
Osteoporosis in the coal miners under different working environment:A comparative study
  
DOI:10.3969/j.issn.1006.7108.2015.08.023
中文关键词:  骨质疏松  维生素D  骨密度;甲状旁腺激素  矿工
英文关键词:Osteoporosis  Vitamin D  Bone mineral density  Parathyroid hormone  Miner
基金项目:
作者单位
刘志奎* 马駿驰 马震胜 张越 高庆峰 刘子洪 河北联合大学附属开滦总医院骨科河北唐山063000 
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中文摘要:
      目的 通过比较煤矿井上井下工人维生素D和骨密度,探究不同工作环境对骨质疏松症发生的影响。方法 采用对照研究的方法,前瞻性选择开滦集团唐山矿工人共计120名,其中井下男性工人60名,年龄在45?55岁;井上男性工人60 名,年龄在45?55岁。通过检测两组矿工25-羟维生素D含量及腰椎和髋部的骨密度值,比较不同工作环境下煤矿矿工骨质疏松发生情况。结果 井上井下矿工年龄、工作时间、体重指数、吸烟、饮酒、血钙、碱性磷酸酶、血尿素氮等基本情况具有一致 性和可比性;与井上矿工相比,井下矿工静脉血甲状旁腺激素含量高(P <0. 05),而静脉血维生素D含量低(P <0. 05).包括腰椎和股骨颈骨密度均低(P <0. 05)。井下矿工骨质疏松占井下矿工总数的8. 3% ,骨量减低占40% ;井上矿工骨质疏松占井上矿工总数的5%,骨量减低占26. 7%。井下矿工维生素D缺乏占井下矿工总数的85% ,维生素D减低占10% ;井上矿工维生素D缺乏占井上矿工总数的18. 3% ,维生素D减低占11. 7%。结论 井下矿工维生素D和骨密度均低于井上矿工。
英文摘要:
      Objective To compare the levels of vitamin D and bone mineral density between the underground and upground workers in the coal mine, for exploring the effect of the different working environment on the occurrence of osteoporosis. Methods Using prospective control method, a total of 120 workers in Kailuan Tangshan mine were selected, including 60 male underground workers (45 -55 years old) and 60 male upground workers (45 -55 years old). The levels of vitamin D and bone mineral density of the lumbar spine and the hip were detected to compare the occurrence of osteoporosis between coal miners under different working environment. Results The basic situation including age, working time, body mass index, smoking, alcohol drinking, calcium, alkaline phosphatase, and blood urea nitrogen between the two groups were consistent and comparable. Serum parathyroid hormone in the upground workers were lower than those in the underground workers (P <0.05), but the vitamin D, and bone mineral density of the lumbar spine and femoral neck in the upground workers were higher than those in the underground workers (P < 0.05). The incidence of osteoporosis and osteopenia was 8. 3% and 40% in the underground miners, and 5% and 26. 7% in the upground miners, respectively. The vitamin D deficiency and insufficiency accounted for 85% and 10% in the underground miners, and 18. 3% and 11. 7% in the upground miners. Conclusion The levels vitamin D and bone mineral density were lower in the underground miners than in the upground miners.
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