全身骨密度与肌肉、脂肪的相关性分析
Correlation analysis among bone mineral density,muscle,and fat of the body
  
DOI:10.3969/j.issn.1006.7108.2015.09.008
中文关键词:  体质量指数  肌肉  脂肪  骨密度  骨质疏松症
英文关键词:Body mass index  Muscle  Fat  Bone mineral density  Osteoporosis
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作者单位
郭郡浩* 姚茹冰 赵智明 林彤彤 杨路昕 蔡辉 南京军区南京总医院中西医结合科江苏南京210002 
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中文摘要:
      目的 旨在进一步分析脂肪、肌肉与骨密度的相关性。方法 200例受检者,男性62例,女性138例,年龄20~84 (48. 9 ± 14. 2) y,体质量 42. 5 ~ 112. 0(61. 29 ± 9. 89) kg,BMI 15. 62~33.58( 23. 03 ± 2. 93) kg/ m2,应用 DXA (dual-energy X-ray absorptiometry,DXA)测量全身骨密度、肌肉、脂肪,并分析全身骨密度与肌肉、脂肪的相关性。结果 200例受检者,全身骨密度与体重、BMI的相关性有统计学意义(分别为r = 0. 530,P<0. 01;r = 0. 221,P<0.01),进一步分析发现,全身骨密度与肌肉呈正相关(r =0. 559,P < 0. 01),与脂肪的相关性无统计学意义(r =0. 018,P = 0. 803)。按性别分析,62例男性,全身骨密度与肌肉、脂肪均呈正相关(r =0. 535,P <0. 01;r =0.274,P = 0. 031)。138例女性,全身骨密度与肌肉呈正相关(r =0. 506,P < 0.01),而与脂肪的相关性无统计学意义(r =0. 088,P =0. 305)。结论(1)全身骨密度与体重、体质量指数呈正相关,其中,起主要作用的是肌肉组织,体现了“骨肉相连”的规律。(2)全身骨密度与脂肪的关系,在男性有相关性,而在女性无相关性, 体现了“男女有别”的规律。
英文摘要:
      Objective To analyze the correlation among fat,muscle,and bone mineral density (BMD). Methods Two hundred people were selected,including 62 males and 138 females. Their age was from 20 to 84 years old (48. 9 ± 14. 2),body mass from 42. 5 to 112. 0 kg (61. 29 ± 9. 89),and BMI from 15. 62 to 33. 58 kg/m2 (23. 03 ± 2. 93). BMD,muscle,and fat of the body were measured using dual-energy X-ray absorptiometry (DXA). The correlation among BMD,muscle and fat was analyzed. Results The correlation between BMD and body weight,BMD and BMI was statistically significant in the 200 cases (r = 0. 530, P <0.01; r =0. 221,P <0. 01 respectively). BMD was positively correlated with body muscle (r =0. 559,P <0. 01),but was not correlated with fat (r = 0.018,P =0. 803). BMD was positively correlated with muscle and fat in 62 males ( r = 0. 535,P <0.01; r = 0. 274,P =0.031,respectively). BMD was positively correlated with muscle in 138 females ( r = 0. 506,P < 0. 01),but was not correlated with fat ( r = 0. 088,P = 0. 305). Conclusions (1) BMD is positively correlated with body weight and BMI. Muscle tissue plays a major role,indicating the rule of close relationship between flesh and bone. (2) BMD is correlated with body fat in men but not in women, indicating the rule of the difference between men and women.
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