1088例医务人员骨质疏松的流行病学研究
The study of prevalence of osteoporosis in 1088 medical workers
  
DOI:10.3969/j.issn.1006-7108.2015.10.013
中文关键词:  医务人员  骨质疏松  危险因素
英文关键词:Medical workers  Osteoporosis  Risk factors
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李冲1 吕伟华2 王亭亭1 邢玉荣2 张丽侠1 刘晓钢1 王志芳1 郑丽丽1* 1. 郑州大学第一附属医院内分泌科河南 郑州 450052 2. 河南省医学会河南 郑州450003 3. 郑州大学第一附属医院体检中心河南 郑州 450052 
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中文摘要:
      目的 通过对我院医务人员体检,了解本院骨质疏松的流行病学情况,分析骨质疏松相关危险因素。方法 选取2014年7月~9月在我院体检的40岁以上在职和离退休医务人员1088例,采用双能X线骨密度仪(DXA)测腰椎(L1-4)、股骨颈、Ward区、大转子区的骨密度。测定空腹血糖、糖化血红蛋白、胆固醇( TC)、甘油三脂( TG)、低密度脂蛋白( LDL- C)、高密度脂蛋白( HDL- C),结合性别、年龄、科室、体重指数(BMI)等因素进行研究。按年龄、性别进行分组,以10岁作为1个年龄段。结果 1.骨质疏松总患病率27.8% (其中女性30.6%,男性21.1%)。2.脂代谢异常占60.11%,糖代谢异常占16.54%。3.女性骨质疏松患病率随年龄上升而增加。不同年龄组的OP患病率差异有统计学意义(P<0.05)。4.离退休医务人员骨质疏松患病率最高(38.8%),外科医生最低(16.9%)。5.Logistic回归分析显示:高BMI值是骨质疏松的保护因素。结论 与普通人群相比,我院医务人员骨质疏松患病率较高,增龄和低BMI是骨质疏松的主要危险因素。
英文摘要:
      Objective To assess the prevalence of osteoporosis and related risk factors of medical workers in our hospital by health screening examination. Methods A total of 1088 medical workers aging above 40 years old who had physical examination in our hospital from July to September 2014 were selected. The bone mineral density (BMD) of the lumbar vertebrae 1-4 (L1-4 ) and the proximal region of the femur including neck, Ward triangle, and Troch was detected using dual energy X-ray absorptiometry (DEXA). Meanwhile, the serum levels of FBG, HbAlc, TC, TG, LDL- C, and HDL- C were also measured and analyzed combining with factors including sex, age, department, and body mass index (BMI). They were divided into groups of 10-year division. Results The prevalence of osteoporosis in medical workers over 40 years old was 27.8% (30.6% in females, 21.1% in males). The prevalence of dyslipidemia was 60.11% and impaired glucose metabolism was 16.54%. With the increase of age, the prevalence of osteoporosis increased in women, with significant difference among different age groups (P<0.05). The prevalence of osteoporosis in retired medical workers was the highest (38.8%), while in surgeons it was the lowest (16.9%). Logistic regression analysis showed that high BMI was the protective factor of osteoporosis. Conclusion The prevalence of osteoporosis in medical workers is higher than that in normal people. Aging and low BMI are the main risk factors of osteoporosis.
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