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| 骨密度和25羟维生素D在骨质疏松性髋部骨折的作用 |
| The effect of bone mineral density and 250HD on the osteoporotic hip fracture |
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| DOI：10.3969/j.issn.1006.7108.2015.12.007 |
| 中文关键词: 骨质疏松 髋部骨折 骨密度 25羟维生素D |
| 英文关键词:Osteoporosis Hip fracture Bone mineral density 25OHD |
| 基金项目:福建省医药卫生科技创新项目（2015-CXB-18);泉 州市科技项目（2014Z44) |
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| 中文摘要: |
| 目的 在股骨颈骨密度达到骨质疏松阈值的情况下，比较髋部骨折与无髋部骨折患者的年龄、骨密度和25羟维生素 D,了解这些因素对髋部骨折的影响。方法 对137例骨密度达到骨质疏松阈值的绝经后女性患者进行研究，无髋部骨折组 62例，髋部骨折组75例，检测股骨颈骨密度和血清25羟维生素D,比较二组年龄、股骨颈骨密度和25羟维生素D水平。结果 无髋部骨折组：年龄：（67. 92 ±8. 52)岁，股骨颈骨密度：（0. 5064 ±0. 0706)g/cm2,T 值：-3. 10 ±0. 60,25OHD： (24. 90 ± 8. 98)ng/ml。髋部骨折组：年龄：（78. 49 ± 8. 52)岁，股骨颈骨密度：（0. 4506 ± 0. 0983 ) g/cm2,T 值：-3. 51 ± 1. 18, 25OHD： (l4.89±8.94)ng/ml。结论 在股骨颈骨密度达到骨质疏松阈值的情况下，髋部骨折患者具有更高年龄，更低骨密度和25羟 维生素D。 |
| 英文摘要: |
| Objective To compare age, bone mineral density, and 25OHD between the osteoporotic patients with and without hip fractures for understanding influence of these factors in the hip fracture. Methods There were 137 postmenopausal women with BMD under -2. 5 SD in the femoral neck in our series, including 62 patients without hip fracture and 75 patients with hip fracture. BMD measurement of femoral neck and serum 25OHD were examined. Age, BMD, and 25OHD were compared between the patients with and without hip fractures. Results The age，BMD of the femoral neck, T score, and 25OHD were 67. 92 ±8.52 yrs, 0. 5064 ± 0. 0706 g/cm2, - 3. 10 ± 0. 60, and 24. 90 ± 8. 98 ng/ml, respectively, in the osteoporotic patients without hip fracture. They were 78.49 ± 8. 52 yrs, 0. 4506 ± 0. 0983 g/cm2, - 3. 51 ± 1. 18，and 14. 89 ± 8. 94 ng/ml, respectively, in the osteoporotic patients with hip fracture. Conclusion Under the condition of -2. 5 SD of femoral neck BMD，the patients with hip fracture are older, lower in femoral neck BMD and 25OHD than the patients without hip fracture. |
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