| Bone remodeling is a dynamic equilibrium between bone resorption and bone formation. Previous studies on bone reconstruction have mainly focused on orthopedic autocrine, paracrine, and so on. In recent years, the research on neural regulation and bone reconstruction has increased significantly. Progress has been achieved and the clinical application has also been recognized. By referring to domestic and foreign literatures, this paper summarizes the effect of neural regulation on bone remodeling, from the aspects of sympathetic nervous system, the parasympathetic nervous system, leptin, neuropeptide, and serotonin, etc.，in order to provide reference for further study of neural regulation in the musculoskeletal field. |