维生素D受体基因多态性与冠心病的相关性
Correlation between vitamin D receptor gene polymorphism and coronary heart disease
  
DOI:10.3969/j.issn.1006.7108.2015.12.025
中文关键词:  维生素D受体  基因多态性  冠心病
英文关键词:Vitamin D receptor  Gene polymorphisms  Coronary artery disease
基金项目:
作者单位
潘楠楠 孟佳 迟啸威 姜礼红* 哈尔滨医科大学附属第二医院,哈尔滨150001 
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中文摘要:
      近年来国内外研究均证实维生素D能够抑制炎症反应程度,从而具有延缓冠状动脉粥样硬化的作用,而维生素D的作用通过维生素D受体来实现,现已知维生素D受体基因存在变异,而这些变异可能影响维生素D的作用。本文拟就维生素D 及其受体基因变异与动脉硬化相关心血管疾病的关系进行综述。
英文摘要:
      In recent years, national and international studies have confirmed that vitamin D can inhibit inflammatory reaction, therefore has anti-atherosclerosis effect. The effect of vitamin D is through vitamin D receptors. It is known that the presence of the vitamin D receptor gene mutation may affect the role of vitamin D. This paper reviews the vitamin D receptor gene variant and its relation to atherosclerosis -related cardiovascular disease.
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