| Objective To observe the changes of serum alkaline phosphatase (ALP), total calcium (TCa), and phosphorus (P) after the treatment with Xianlinggubao capsule in elderly women with Colles fracture, and to evaluate its clinical efficacy. Methods A total of 124 patients were divided into treatment group and control group, with 62 cases in each group. At the second day, 4- week, 8-week, and 12-week after the treatment, fasting scrum ALP, TCa, and P were detected and the callus growth was observed with X-ray. Results ALP was higher in the treatment group than that in the control group at the 4- and 8-week (P<0. 01)，but it was lower at the 12-week than that in the control group. TCa of treatment group was significantly higher than that in the control group at 4-week (P <0. 01) , but it was lower than that in the control group after 8 weeks. P level in the treatment group was higher than that in the control group at 4- and 8-week ( P < 0. 01)，and it was similar at 12 weeks. The callus score in X-rav was significantly higher in the treatment group than that in the control group at 4-，8-, and 12-week (P< 0. 01 ). Conclusion Xianlinggubao capsule can affect the serum ALP, TCa, and P, promote the blood circulation of the fracture zone, and stimulate the calcium deposition and callus formation, resulting in promotion of fracture healing. |