| The prevalence of osteoporosis is high in the elderly people, and it seriously affects the life quality of the elderly population. With aging of the global population, the prevention and treatment of osteoporosis has become a focus of the world. This paper analyzes 995 published literatures by scholars in Guangdong province in recent 5 years, and compares with those published 5 years ago. It has been found that there is new understanding in epidemiology, indicating that osteoporosis has aroused the attention of clinicians. Studies in animal experiment and pathological mechanism have been mature and decreased. Dual-energy X-ray absorptiometry has been widely used in clinical diagnosis of osteoporosis. Fracture is the most serious complication of osteoporosis. Especially intertrochanteric fractures are common in older adults, with high probability of complication and mortality. Treatment of osteoporotic fracture should consider not only the local fracture process, but also the treatment of osteoporosis to improve the overall curative effect and quality of life. Calcium, vitamin D, alendronates, and salmon calcitonin have been applied in clinical practice. New treatment measures, such as complex vibration, have been applied in clinical treatment. In summary, osteoporosis has aroused wide attention in Guangdong. Diagnosis and treatment are standardized. Osteoporosis can be delayed and prevented if self-health care consciousness and active intervention are improved in a scientific way. It is of important significance to the patients and society. |