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| 纳米压痕检测中保载时间对骨微观弹性模量和硬度影响 |
| The dynamic change of bone hardness and Er as the holding time by nanoindentation |
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| DOI：10.3969/j.issn.1006.7108.2016.03.009 |
| 中文关键词: 纳米压痕 保载时间；微观力学 皮质骨 大鼠 |
| 英文关键词:Nanoindentation Holding time Micromechanics Cortical bone Rats |
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| 中文摘要: |
| 目的 观察不同保载时间对骨微观弹性模量和硬度的影响，探讨SD大鼠合适的保载时间。方法 10只10月龄雌性 SD大鼠，取双侧股骨制备成纳米压痕标本。采用纳米压痕技术分别在不同保载时间下（分为15 s,30 s,60 s,90 s,120 s五组） 测量皮质骨的微观硬度和弹性模量。结果 随着保载时间的增加，在15 s，30 s,60 s时硬度和弹性模量有递增趋势，在60 s 之后有下降趋势或者反折。硬度H组间P>0.05,无显著性差异；弹性模量Er组间P<0.05，有显著性差异。结论 60 s是 SD大鼠合适的保载时间。为更准确的测量大鼠微观力学特性提供了理论依据。 |
| 英文摘要: |
| Objective To discuss the best holding time for the SD rats by the dynamic change of the micro biomechanical properties of hardness and elastic modulus as the holding time changes. Methods Ten female SD rats aged ten months were divided into 5 groups：15 s group, 30 s group, 60 s group，90 s group, 120 s group. Their bilateral femurs were prepared into nanoindentation specimens. The hardness and elastic modulus of the specimens were measured by nanoindentation. Results As the increase of the holding time, the curves of the hardness and elastic modulus of the cortical specimens were increasing on the holding time of 15 s, 30 s and 60 s. But the curves of the hardness and elastic modulus were opposite on the holding time of 90 s and 120 s. Therr is no significant difference in each Hardness groups (P < 0.05). There is the significant difference in each Er groups(P< 0. 05). Conclusion 60 s is the best holding time for the SD rats by nanoindentation. It provides the theory basis for measuring the micromechanics properties in rats. |
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