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| 2型糖尿病患者颈动脉粥样硬化与骨密度的相关性研究 |
| The correlation between carotid atherosclerosis and bone mineral density in type 2 diabetic patients |
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| DOI：10.3969/j.issn.1006.7108.2016.03.010 |
| 中文关键词: 2型糖尿病 颈动脉粥样硬化 颈动脉内膜中层厚度；骨密度 |
| 英文关键词:Type 2 diabetes mellitus Carotid atherosclerosis Carotid artery intima-media thickness Bone mineral density |
| 基金项目:国家临床重点专科建设项目资助（2011);重庆市卫生局科研基金资助项目（12-02-041) |
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| 中文摘要: |
| 目的 探讨2型糖尿病（T2DM)患者颈动脉粥样硬化（CA)与骨密度（BMD)的相关性。方法 选取T2DM患者201例，根据颈动脉内膜中层厚度（IMT)分为正常组和动脉粥样硬化组。测量血压、身高、体重，并检测生化指标,采用彩色多谱勒超声测定颈动脉IMT,双能X线吸收仪（DXA)测定腰椎1-4、股骨颈、股骨转子、Ward’s和全髋部的骨密度。结果 男性T2DM 患者动脉粥样硬化组L1、Ward’s骨密度均低于正常组，差异均有统计学意义（P <0.05)。女性T2DM患者动脉粥样硬化组 L1、L2、L3、L1-4、Ward’s、全髋部的骨密度均低于正常组，差异均有统计学意义（P <0. 05 )。Pearson相关分析显示T2DM患者颈动脉IMT与各部位骨密度均成负相关。结论 T2MD患者颈动脉粥样硬化与骨密度密切相关。 |
| 英文摘要: |
| Objective To evaluate the correlation between carotid atherosclerosis (CA)and bone mineral density(BMD) in type 2 diabetic(T2DM) patients. Methods 201 T2DM patients were divided into normal group and atherosclerotic group according to their IMT. Their blood pressure, body height,body weight and biochemical indexes were measured. Their carotid IMT was measured by ultrasongraphy. The L1，L2，L3，L1-4，neck, troch, Ward’s and total bone mineral density was measured by Dual energy X-Ray absorptiomtry( DXA). Results The L1, and Ward’s bone mineral density was significantly lower in atherosclerotic group than that in normal group in male patients with T2DM (P < 0. 05 ). The L1, L2, L3, L1-4, Ward ’ s and total bone mineral density was significantly lower in atherosclerotic group than that in normal group in female patients with T2DM( P < 0. 05). Pearson correlation analysis showed that the carotid IMT was negatively related with all bone mineral density in T2DM patients. Conclusion The carotid atherosclerosis is closely correlated with the bone mineral density in T2DM patients. |
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