藏族成人骨强度与体成分关系研究
Association of bone strength and body composition of adult tibetans
  
DOI:10.3969/j.issn.1006.7108.2016.03.022
中文关键词:  藏族成人;骨强度;骨质疏松症;体成分  超声骨密度;生物电阻抗分析
英文关键词:Tibetans  Bone strength  Osteoporosis  Body composition  Ultrasonic bone mineral density meter  Bioelectric impedance technique
基金项目:科技部基础专项(2012FY110900);国家自然科学基金(31460271 );中央高校基本科研业务费专项资金项目 (31920130044;31920130040)
作者单位
杨秀琳 海向军* 何烨 何进全 马力扬 窦春江 西北民族大学医学院兰州730030 
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中文摘要:
      目的 分析藏族成人骨强度分布特点及其与体成分之间的关系,为完善我国不同民族骨质相关数据并找出合理的防治骨质疏松症方法提供依据。方法 采用整群抽样法抽取西藏藏族自治区日喀则市,甘肃省甘南藏族自治州、天祝藏族自治县藏族成年居民共817名,采用超声骨密度仪及生物电阻抗分析仪分别测量受试者右足跟骨骨强度及体成分相关指标,采用多元逐步回归法分析骨强度与体成分各指标之间的关系。结果 藏族成年男性、女性骨强度分别在18~29岁、30~39岁达 到峰值,之后随年龄增长骨强度下降;60岁之后男性骨强度高于女性,差异有统计学意义(P <0.001);甘肃藏族成人骨量异常的发生高于西藏藏族(χ2 =4. 097,P =0.044);多元线性回归分析显示,肌肉量、皮下脂肪量及内脏脂肪量为藏族成人骨强度的影响因素(P =0. 000)。结论 藏族成人骨强度在30岁左右达到峰值,50岁后女性是OP的危险人群;甘肃藏族成人患OP的危险性高于西藏藏族成人;肌肉量及皮下脂肪量是OP发病的保护性因素,而内脏脂肪量是OP发病的危险因素。
英文摘要:
      Objective Analyzing the distribution of bone strength of adult Tibetans and its relationship with body composition to complete the bone health related data of different races in China, and to provide scientific basis for osteoporosis (OP) protection policy making. Methods Ultrasonic bone mineral density meter and Bioelectric impedance technique were used to test the bone strength of right calcaneus and body composition of cluster sample of 817 adult Tibetans living in Shigatse, Tianzhu Tibetan Autonomous County and Gannan Tibetan Autonomous Prefecture. The association of bone strength and body composition were tested by using Multiple Linear Regression. Results The peak bone strength of Tibetans male and female are reached at 18 - 29 and 30 - 39 years old respectively. The bone strength of male are higher than female after 60 years old, the differences have statistical significance(P < 0. 001). The incidence of bone mass abnormal in Gansu Tibetans was higher than Tibetans in Tibet(χ2 = 4. 097 = 0. 044). According to the results of Multiple Linear Regression,muscle mass,subcutaneous fat mass and visceral fatmass were related factors of bone strength of adult Tibetans (P =0.000). Conclusion The bone strength of Tibetans reach maximum at about 30 years old; female Tibetans ≥50 years old are high risk population of OP;the Gansu Tibetans were more likely to suffer OP. Muscle mass and subcutaneous fat mass are protective factors of OP while visceral fat mass is risk factor of OP.
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