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| 骨代谢异常与泌尿系结石 |
| Abnormal bone metabolism and urinary calculus |
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| DOI：10.3969/j.issn.1006.7108.2016.04.025 |
| 中文关键词: 骨密度 高钙尿 泌尿系结石 生化指标 |
| 英文关键词:Bone mineral density Hypercalciuria Urinary calculus Biochemical indicators |
| 基金项目:南京市医学重点科技发展项目（ZKX12016);南京市卫生局项目（YKK13079);江苏省人社厅“六大人才髙峰”资助项目 (2015-wsw-066) |
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| 中文摘要: |
| 骨代谢异常患者其泌尿系结石的发病风险增加，而泌尿系结石患者亦常伴有不同程度的骨质流失。高钙尿是骨密度 (Bone mineral density，BMD)降低的重要临床表现，同时也是泌尿系结石的重要病因，其或是连接骨代谢异常与泌尿系结石的纽带。通过观察一些生化指标的变化，可以评估骨密度情况及结石发生风险。及时纠正髙钙尿对防止BMD的降低和结石的发生都有帮助。本文就骨代谢异常、高钙尿及泌尿系结石三者之间的关系、生化指标的改变及针对性的治疗作一综述。 |
| 英文摘要: |
| Patients with abnormal bone metabolism have an increasing risk of urinary calculus, while those with urinary calculus are often accompanied with certain degree of bone loss. Hypercaciuria is not only a crucial manifestation of the decrease of bone mineral density (BMD)，but also an important cause of urinary stone. It may be a potential link between bone metabolism disorder and urinary stone. The change of certain biochemical indicators may evaluate BMD and risks of the recurrence of urinary stone. Correction of hypercalciuria can prevent BMD decrease and occurrence of urinary stones. In this article， we have reviewed the interaction among bone metabolism disorder, hypercalciuria, urinary calculus, the alternation of biochemical indicators, and the specific treatment. |
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