| Primary osteoporosis includes postmenopausal osteoporosis and senile osteoporosis. The disease can lead to severe osteoporotic fractures. Patients may have fractures in corresponding location after mild trauma. Common fracture sites include the spine, hip, and forearm. Among them, fractures in the spine and hip can significantly increase rates of disability and mortality. The number of women who have fracture due to osteoporosis is more than the sum of female patients with heart disease，stroke，and breast cancer. Osteoporosis not only affects the physical and mental health and quality of life, but also leads to huge medical consumption. Therefore it is important to gradually elucidate the cause of the disease. Scholars have found that the cause of primary osteoporosis is associated with endocrine factors, genetic factors, nutritional status, physical factors, way of life, and psychological status. In this paper, the research progress in the etiology of primary osteoporosis is summarized by relevant literature review. |