| Objective To explore the factors that can predict osteoporosis in postmenopausal women with rheumatoid arthritis (RA). Methods The general clinical data of 100 postmenopausal women with RA were collected, including age, course of disease，erythrocyte sedimentation rate ( ESR) , C-reactive protein ( CRP)，rheumatoid factors ( RF) , anti-cyclic citrullinated peptide antibody, the number of joint pain, and the number of joint swelling. Bone mineral density (BMD) of the lumbar vertebrae and the hip were measured using dual energy X-ray absorptiometry. The data were compared and the potential related factors were analyzed. Results (1) The ratio osteoporosis, osteopenia, and normal bone mass in postmenopausal women with RA were 33%,47% , and 20% , respectively. (2) Patients in osteoporotic group had older age, longer course, more joint pain, and higher HSR and DAS28 than those in non-osteoporotic group. (3) Logistic regression analysis showed that age and DAS28 were independent factors of BMD in postmenopausal women with RA. (4) Based on the ROC curve, the optimal cut-point of DAS28 related to osteoporosis was 5. 3. The cut-point of age was 59. 5 years old. Conclusion DAS28 and age have strong predictive effect on osteoporosis in postmenopausal women with RA. |