| Osteoblasts, being the stress feeling and targeting cells, play an important role in the growth, repair, and remodeling of the bone. Therefore, it is important to study the effect and mechanism of different stress stimulation on the osteoblast. The mechanical stimulation loaded on osteoblast can be tension, fluid shear stress, and compressive stress. The study of bone effect under various stress conditions is gradually increasing. This paper reviews the research progress in the effect of different stress stimulation to the function of the osteoblast, the response of the osteoblast to the external force, and the signal transduction pathway involved in the process. |