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| 脂代谢及血清骨钙素水平与骨质疏松症的相关性分析 |
| The correlation analysis between the level of lipid metabolism and osteocalcin and osteoporosis |
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| DOI：10.3969/j.issn.1006-7108.2016.06.011 |
| 中文关键词: 骨质疏松症 脂代谢 血清骨钙素 |
| 英文关键词:Osteoporosis lipid metabolism Osteocalcin |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨脂代谢与血清骨钙素（osteocalcin，OSC ；bone glaprotein，BGP）水平与骨质疏松症的相关性。方法 选取2014年3月至2015年3月我院风湿科门诊患者及体检科收治的体检者，观察组为418例确诊骨质疏松症患者，对照组为无骨质疏松症状的396例健康者。分析两组患者脂代谢及血清骨钙素水平与骨质疏松症相关性。结果 观察组的总胆固醇（TC）、甘油三酯（TG）和低密度脂蛋白（LDL-L）高于对照组， 高密度脂蛋白（HDL-L）水平、血清骨钙素水平降低，具统计学意义，且骨钙素和TG呈负相关。结论 脂代谢障碍、血清骨钙素的减少具有影响骨代谢、加快骨吸收的作用，并由此影响骨质疏松症的发病。 |
| 英文摘要: |
| Objective To study the correlation between the level of lipid metabolism and osteocalcin (OC) and osteoporosis. Methods A total of 814 patients in our hospital from March 2014 to March 2015 were selected. Among those, 418 patients with osteoporosis were enrolled in the observation group and 396 non-osteoporosis people were enrolled in the control group. The level of lipid metabolism and OC and their correlation with osteoporosis were analyzed. Results The levels of TC, TG, and LDL-L in the observation group were higher, but HDL-L and OC were lower than those in the control group. The difference was significant (P<0.05). OC was negatively associated with TG. Conclusion Disorder of lipid metabolism and reduction of OC play a role in bone metabolism, which is important in the pathogenesis of osteoporosis. |
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