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| 围绝经期女性雌激素水平与“血瘀”相关性的研究 |
| The study of correlation between estrogen level and blood stasis in the perimenopausal women |
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| DOI：10.3969/j.issn.1006.7108.2016.07.014 |
| 中文关键词: 围绝经期 雌激素 血瘀 相关性分析 |
| 英文关键词:Perimenopause Estrogen Blood stasis Correlation analysis |
| 基金项目:福建省医学创新课题（2012-CXB-26) |
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| 中文摘要: |
| 目的 探讨围绝经期女性雌激素水平与“血瘀”的关联性。方法 132例符合纳入标准的围绝经期女性按年龄每5岁为一组，分为4组，分别检测雌二醇（E2)、血液流变学指标，并对其进行“血瘀”量化评分、甲襞微循环评分,相关数据采用多元回归等统计学进行分析。结果 围绝经期女性随年龄递增雌激素水平变化与血瘀量化评分、甲襞微循环评分存在显著的负相关（P <0.01);与全血粘度、红细胞刚性指数等存在显著负相关（P <0.01)，与全血还原粘度存在负相关（P <0. 05)，与红细胞电泳时间存在显著正相关（P<0.01)。结论 围绝经女性雌激素水平与“血瘀”表达呈负相关，围绝经期女性雌激素水平的变化是导致其血瘀证的重要因素之一。 |
| 英文摘要: |
| Objective To discuss the correlation between estrogen level and blood stasis in perimenopausal women. Methods One hundred and thirty-two perimenopausal women who met the inclusion criteria were divided into 4 groups by every five years of age. Estradiol and hemorheology were detected. The quantitative stasis score, microcirculation score, and the relevant data were analyzed using multivariate regression analysis. Results Estrogen level was negatively correlated with blood stasis quantitative score and with microcirculation score with the age increase in perimenopausal women. It was also negatively correlated with whole blood viscosity, with erythrocyte rigidity index, and erythrocyte electrophoresis time (P <0. 01). Conclusion Estrogen level was negatively correlated with the expression of blood stasis in perimenopausal women. The change of estrogen level in perimenopausal women is one of the important factors leading to blood stasis syndrome. |
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