Adefovir dipivoxil (ADV) is an oral bioavailable prodrug of adefovir, which is a phosphonate acyclic nucleotide analogue of adenosine monophosphate. It has antiviral effect, and has been used for the treatment of AIDS. ADV at low doses can induce nephrotoxicity. In this article, we presented a case of osteomalacia induced by Adefovir dipivoxil, and reported its diagnosis and treatment, with the aim to improve future diagnosis and treatment of this disease. |