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| 糖尿病患者骨代谢的变化及运动对其影响的研究进展 |
| Research progress in bone metabolism and the effect of exercise on it in diabetic patients |
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| DOI：10.3969/j.issn.1006.7108.2016.11.027 |
| 中文关键词: 糖尿病 骨质疏松 高血糖 胰岛素；瘦素 脂联素 运动 |
| 英文关键词:Diabetes mellitus Osteoporosis Hyperglycemia Insulin Leptin Adiponectin Exercise |
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| 中文摘要: |
| 糖尿病主要是以胰岛素分泌缺陷或胰岛素作用障碍导致的以高血糖为主的代谢性疾病。大量的临床研究及动物研究证实,糖尿病患者骨代谢易紊乱，多发骨质疏松等疾病。胰岛素分泌对骨代谢具有十分重要的作用。本文分别从高血糖环境、胰岛素及髙血脂环境对糖尿病患者骨代谢的影响进行详细综述,探讨其影响骨代谢、造成骨质疏松的相关机制。此外,通过分析运动改善糖尿病患者骨代谢，为体育锻炼防治糖尿病患者骨质疏松等疾病提供基础理论参考。 |
| 英文摘要: |
| Diabetes mellitus is a metabolic disease that is mainly due to the secretion defect and function obstacle of insulin, resulting in hyperglycemia. Most clinical research and animal experiments find that diabetes mellitus can easily cause disturbance of bone metabolism, resulting in osteoporosis. The secretion of insulin plays an important role in bone metabolism. This article summaries the reasons resulting in diabetic osteoporosis from the aspects of hyperglycemia environment, insulin, and high fat, and explores the mechanism of the effect on bone metabolism and osteoporosis. Moreover, by analyzing how sports improve bone metabolism in diabetic patients, we provide theoretical basis and reference for the prevention and treatment of diabetic osteoporosis. |
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