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| 子痫前期妇女超声骨密度及血钙分析 |
| An analysis on bone mineral density and blood calcium in women with preeclampsia |
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| DOI：10.3969/j.issn.1006.7108.2016.12.009 |
| 中文关键词: 子痫前期 孕妇 超声检查，产前 骨密度 妊娠期高血压疾病 钙 |
| 英文关键词:Preeclampsia Pregnant women Ultrasonography, prenatal Bone mineral density Hypertensive disorders of pregnancy Calcium |
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| 中文摘要: |
| 目的 研究子痫前期妇女骨密度情况及血钙水平与正常孕妇有无差异。方法 回顾性病例分析，入组单胎孕妇270人，其中诊断子痫前期者150人，为子痫前期组，包括轻度子痫前期与重度子痫前期，无子痫前期及妊娠期高血压诊断者120人，为对照组。査询所有孕妇早孕期超声骨密度结果，早孕及晚孕生化检査，包括血钙、铁的检测。结果 子痫前期组骨密度超声波传导速度（speed of sound, SOS)值明显低于对照组（t= -2. 052,P=0. 043)，骨密度T值明显低于对照组（t =-2. 041 ,P = 0.044)，子痫前期组早孕期血钙与对照组无差异，晚孕期血钙低于对照组（t= -2.247，P=0.016)。早孕期及晚孕期血铁水平无统计学差异。结论 孕早期的超声骨密度检査及孕期的血钙等生化指标测定，对于子痫前期有一定的预测意义。 |
| 英文摘要: |
| Objective To investigate the differences in bone mineral density and blood calcium between women with preeclampsia and normal pregnancy. Methods Retrospective case analysis was performed in 270 single birth gravida, who were divided into two groups：the preeclampsia group had 150 women who were diagnosed preeclampsia, while the control group had 120 women without preeclampsia and gestational hypertension. All pregnant women had ultrasound bone mineral density examination in early pregnancy using ultrasound bone densitometer. In addition, biochemical tests were performed in early and late pregnancy, which included calcium and iron concentration. Results The ultrasound bone mineral density of the preeclampsia group was significantly lower than that of the control group. The preeclampsia group’s early pregnancy blood calcium was not statistically different from that of the control group, whereas the preeclampsia group’s late pregnancy blood calcium was lower than that of the control group. The two groups，serum iron concentrations in early and late pregnancy were not significantly different. Conclusion The early pregnancy ultrasound bone mineral density and the blood calcium concentration have certain significance in predicting preeclampsia. |
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