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| 维生素D与动脉粥样硬化相关性研究进展 |
| Research progress on the relationship between vitamin D and atherosclerosis |
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| DOI：10.3969/j.issn.1006.7108.2016.12.028 |
| 中文关键词: 维生素D 动脉粥样硬化 炎症反应 肾素-血管紧张素系统 |
| 英文关键词:Vitamin D Arteriosclerosis Inflammatory reaction Renin angiotensin system |
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| 中文摘要: |
| 关于维生素D的生物学效应除了调节钙磷代谢、骨质钙化外，最新研究发现，维生素D对其他多种非骨代谢疾病也同样存在着密切关系。越来越多的基础及临床研究证实，维生素D可以通过多条途径参与及影响动脉粥样硬化的形成，如炎症反应、肾素-血管紧张素系统及胰岛素的分泌与抵抗等。因此，维生素D缺乏可能导致罹患动脉粥样硬化的风险增加。本文就维生素D可能参与动脉粥样硬化发病机制及相关临床研究作一综述。 |
| 英文摘要: |
| Recent studies found that vitamin D have multiple biological effects. Besides regulation of calcium-phosphorus metabolism and bone calcification, it has also been associated with non-bone metabolic diseases. An increasingly number of basic researches and clinical trials have shown that vitamin D could affect and involve in many pathways on the formation of atherosclerosis, including inflammatory reaction, renin - angiotensin system, and insulin secretion and resistance. Therefore, we could learn from these researches that vitamin D deficiency is linked to a higher risk of atherosclerosis. This article reviewed on the research progress on the relationship between the vitamin D and atherosclerosis. |
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