| Objective To study the prevalence and risk factors of osteoporotic fractures in Guiyang residents aged 40 years old and above, and to provide a theoretical basis for the prevention and treatment of osteoporotic fractures in the area. Methods A total of 8960 adults, aged 40 to77 years old, living in the Yunyan community in Guiyang of Guizhou, were randomly selected from May 2011 to October 2011. All of them were investigated with questionnaire, physical examination, and ultrasonic bone mineral density measurement. The follow-up rate was 63.58%. Diagnostic criteria for osteoporosis fracture were the self-reported history of brittle fracture or imaging report of fractures. A brittle fracture is defined as a fracture that falls from a standing position or below the height of a standing position to the ground or to a similar degree. Results (1) The incidence of osteoporotic fractures was 4.86% (277 cases, 31 males and 246 females). The main fracture site was the distal forearm, the ankle, and the spine. The incidence in females (5.94%) was significantly higher than that in males (1.99%), and the difference was statistically significant. (2) Female gender (OR=3.427; 95% CI: 1.98-5.93; P<0.001), BMD T-score<–2.5 (OR=2.054, 95% CI: 1.30-3.26; P=0.002), dyslipidemia (OR=1.474, 95% CI: 1.02-2.13; P=0.038), age (OR=1.029, 95% CI: 1.01-1.05; P=0.002) were the significant risk factors. Conclusion The incidence of osteoporotic fracture increases with age, and it is significantly higher in females than in males. Distal forearm is the most common site of the fracture. The increase of age, female gender, dyslipidemia, and BMD T-score<–2.5 are risk factors of the osteoporotic fracture. |