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| 应用双能CT与定量CT对椎体骨密度测量的对照研究 |
| Comparison of bone mineral density measured by quantitative computed tomography and dual energy CT at the lumbar spine |
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| DOI：10.3969/j.issn.1006.7108.2017.02.005 |
| 中文关键词: X线计算机体层摄影；双能量CT 骨密度 |
| 英文关键词:X-ray computed tomography Dual-energy CT Bone density |
| 基金项目: |
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| 中文摘要: |
| 目的 应用双能CT(DECT)及定量CT(QCT)测量腰椎骨密度，评价利用双能CT测量骨密度（BMD)的可行性。方法 对56名志愿者采用DECT检査，获得钙值图，测量骨钙CT值及骨髓CT值，同时应用QCT测量骨密度（BMD),分析骨钙CT 值及骨髓CT值与BMD值的相关性。结果 腰椎椎体骨钙CT值与BMD值呈显著正相关（L1-5椎体Pearson相关系数分别为： r = 0.715,0. 692, 0. 739, 0.673，0.686，P<0.01);骨髓 CT 值与 BMD 值呈正相关（L1-5 椎体 Pearson 相关系数分别为 r = 0. 343 ,0. 315 .0. 439,0. 440,0. 456,L5椎体P<0. 05,其余椎体P<0. 01)。结论 DECT所测量腰椎骨钙CT值及骨髓CT值与 QCT所测BMD值密切相关，可定量反映腰椎BMD变化。 |
| 英文摘要: |
| Objective Lumbar spine bone mineral density was measured by dual energy CT (DECT) and quantitative CT (QCT) , with the aim of assessing the feasibility of using dual energy CT for the measurement of bone mineral density (BMD). Methods Totally 56 volunteers were enrolled and underwent dual energy CT (DECT ) to obtain the CT attenuation value of bone calcium and bone marrow and also underwent quantitative CT (QCT) to obtain BMD at lumbar spine (L1-Ls) in the same scan. The correlation between CT attenuation value of bone calcium and bone marrow with BMD was analyzed. Results The CT attenuation value of bone calcium was significantly positively correlated with BMD at the lumbar spine, the Pearson correlation coefficients of L1-5 vertebral body were r = 0.715, 0.692, 0.739, 0.673, 0. 686, respectively,P <0.001. The CT attenuation value of bone marrow was positively correlated with BMD, the Pearson correlation coefficients of L1-5 vertebral body were r = 0. 343,0. 315,0. 439,0.440,0. 456, respectively (L5 P<0. 05,L1 toL4 P<0.01). Conclusion The CT attenuation value of bone calcium and bone marrow is closely correlated with BMD value measured by QCT at lumbar spine, which can indicate quantitative BMD. |
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